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SLAMF1 Kit ELISA

SLAMF1 Reactivité: Humain Colorimetric Sandwich ELISA 156 pg/mL - 10000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
N° du produit ABIN6720073
  • Antigène Voir toutes SLAMF1 Kits ELISA
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    Reactivité
    • 5
    • 2
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Gamme de detection
    156 pg/mL - 10000 pg/mL
    Seuil minimal de détection
    156 pg/mL
    Application
    ELISA
    Fonction
    Sandwich ELISA for Quantitative Detection of Antigen
    Type d'échantillon
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    Attributs du produit

    Synonyms: CD 150, Cd150, CD150 antigen, Cdw150, Estm51, Ipo 3, IPO-3, Ipo3, Signaling lymphocytic activation molecule, Signaling lymphocytic activation molecule family member 1, Signaling lymphocytic activation molecule family member 1 isoform CRA_a, Signaling lymphocytic activation molecule family member 1 isoform CRA_b, Signaling lymphocytic activation molecule precursor, Slaf1, SLAF1_HUMAN, SLAM family member 1, Slamf 1, Slamf1, SLAMF1 protein

    Background: Signaling lymphocytic activation molecule is a protein that in humans is encoded by the SLAMF1 gene. It belongs to the immunoglobulin gene superfamily. This gene is mapped to 1q23.3. It has found that SLAM is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes and a proportion of B cells, and is rapidly induced on naive T cells after activation. In MV-resistant cell lines, infection with clinical MV and expression of SLAM, but not CD46, caused cytopathic effects (CPE). The expression of SLAM on activated B and T lymphocytes correlates with the pathology of MV infection in humans and monkeys, in which lymphoid organs are the chief sites of MV replication and the binding of MV to SLAM may impair the signaling functions of SLAM in lymphocyte activation and inhibit Th0/Th1 cytokine production, thereby promoting Th2 cytokine production. It has reported that antibody-mediated ligation of SLAM on thymocytes triggered a protein tyrosine phosphorylation signal in T cells in a SAP-dependent manner. This signal also involved SHIP, the adaptor molecules DOK2, DOK1, and SHC and RASGAP.

    Gene Name: SLAMF1

    Production: Natural and recombinant human SLAM. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: A21-K236

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  • Indications d'application

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL human SLAM standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human SLAM standard solution and each sample be measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 156pg/mL-10,000pg/mL

    Volume d'échantillon
    100 μL
    Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Antigène Voir toutes SLAMF1 Kits ELISA
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    Autre désignation
    SLAM - CD150 (SLAMF1 Produits)
    Synonymes
    CD150 Kit ELISA, SLAM Kit ELISA, SLAMF1 Kit ELISA, 4933415F16 Kit ELISA, AA177906 Kit ELISA, CDw150 Kit ELISA, ESTM51 Kit ELISA, IPO-3 Kit ELISA, Slam Kit ELISA, RGD1560634 Kit ELISA, signaling lymphocytic activation molecule family member 1 Kit ELISA, SLAMF1 Kit ELISA, Slamf1 Kit ELISA
    ID gène
    6504
    NCBI Accession
    NP_003028
    UniProt
    Q13291
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