COMT Kit ELISA
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- Antigène Voir toutes COMT Kits ELISA
- COMT (Catechol-O-Methyltransferase (COMT))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 31.2 pg/mL - 2000 pg/mL
- Seuil minimal de détection
- 31.2 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: Catechol O methyltransferase, Catechol O-methyltransferase, COMT, COMT_HUMAN, EC 2.1.1.6
Background: Catechol-O-methyltransferase (COMT) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. In the brain, COMT-dependent dopamine degradation is of particular importance in brain regions with low expression of the presynaptic dopamine transporter (DAT), such as the prefrontal cortex. This process is supposed to take place in postsynaptic neurons, as, in general, COMT is located intracellularly in the central nervous system (CNS).
Gene Name: COMT
Production: Natural and recombinant human COMT. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: E.coli, Immunogen sequence: G52-P271
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- Discover our top product COMT Kit ELISA
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human COMT standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum and plasma (heparin, EDTA) to each empty well. It is recommended that each human COMT standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 31.2pg/mL-2000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes COMT Kits ELISA
- COMT (Catechol-O-Methyltransferase (COMT))
- Autre désignation
- COMT (COMT Produits)
- Synonymes
- Comt1 Kit ELISA, D16Wsu103e Kit ELISA, D330014B15Rik Kit ELISA, COMT Kit ELISA, mb-comt Kit ELISA, s-comt Kit ELISA, comt Kit ELISA, MGC154444 Kit ELISA, zgc:114157 Kit ELISA, si:dkey-13a21.15 Kit ELISA, zK13A21.15 Kit ELISA, zgc:162236 Kit ELISA, catechol-O-methyltransferase Kit ELISA, microRNA 4761 Kit ELISA, catechol-O-methyltransferase S homeolog Kit ELISA, methyltransferase Kit ELISA, catechol-o-methyltransferase Kit ELISA, catechol-O-methyltransferase a Kit ELISA, catechol-O-methyltransferase b Kit ELISA, catechol O-methyltransferase Kit ELISA, COMT Kit ELISA, Comt Kit ELISA, MIR4761 Kit ELISA, comt Kit ELISA, comt.2 Kit ELISA, comt.S Kit ELISA, Rv1703c Kit ELISA, Mb1729c Kit ELISA, comta Kit ELISA, comtb Kit ELISA, LOC100354142 Kit ELISA
- ID gène
- 1312
- NCBI Accession
- NP_000745
- UniProt
- P21964
- Pathways
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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