MBL2 Kit ELISA

N° du produit ABIN6720207

Détail du produit MBL2 Kit ELISA

Antigène: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 312 pg/mL - 20000 pg/mL

Seuil minimal de détection: 312 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytical Method: Quantitative

Attributs du produit:

Synonyms: COLEC1, Collectin-1, Lectin mannose-binding soluble 2, Mannan binding lectin, Mannan binding protein, Mannose binding lectin 2 soluble, Mannose binding lectin 2 soluble, Mannose binding lectin, Mannose binding lectin protein C2 soluble opsonic defect, Mannose binding protein, Mannose binding protein C, Mannose binding protein C precursor, Mannose-binding lectin, MBL, MBL2_HUMAN, MBL2D, MBP 1, MBP, MBP1, MBPB, MBPC, MBPD, Opsonic defect, protein C, Soluble mannose binding lectin

Background: MBL2, also called mannose-binding lectin (protein C) 2, soluble or Mannose-binding lectin (MBL) is a lectin that is instrumental in innate immunity. MBL2 is mapped to chromosome 10q11.2-q21. It belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL2 recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding MBL2 to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL2 is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.

Gene Name: MBL2

Production: Natural and recombinant human MBP-C. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: E21-I248

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 20000pg/mL, 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL human MBP-C standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human MBP-C standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 312pg/mL-20000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Autre désignation: MBP-C - MBL2 (MBL2 Produits)

Synonymes: COLEC1 Kit ELISA, HSMBPC Kit ELISA, MBL Kit ELISA, MBL2D Kit ELISA, MBP Kit ELISA, MBP-C Kit ELISA, MBP1 Kit ELISA, MBPD Kit ELISA, pMBP-27 Kit ELISA, mbl2 Kit ELISA, MBL1 Kit ELISA, cMBl Kit ELISA, collectin Kit ELISA, Ab2-001 Kit ELISA, Ab2-011 Kit ELISA, L-MBP Kit ELISA, MBL-C Kit ELISA, COLEC2 Kit ELISA, mbl Kit ELISA, etID42583.2 Kit ELISA, fb68b07 Kit ELISA, hbl3 Kit ELISA, wu:fb68b07 Kit ELISA, zgc:109836 Kit ELISA, mannose binding lectin 2 Kit ELISA, Mannose-binding protein C Kit ELISA, mannose-binding lectin (protein C) 2, soluble Kit ELISA, mannose-binding lectin (protein C) 2 Kit ELISA, mannose-binding lectin family member 3, pseudogene Kit ELISA, MBL2 Kit ELISA, mbl2 Kit ELISA, Mbl2 Kit ELISA, MBL3P Kit ELISA

ID gène: 4153

NCBI Accession: NP_000233

UniProt: P11226

Pathways: Système du Complément, Positive Regulation of Immune Effector Process