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BIRC7 Kit ELISA

BIRC7 Reactivité: Humain Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Cell Culture Lysate, Cell Culture Supernatant, Serum, Tissue Homogenate
N° du produit ABIN6720313
  • Antigène Voir toutes BIRC7 Kits ELISA
    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
    Reactivité
    • 6
    • 3
    • 2
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Gamme de detection
    0.78 ng/mL - 50 ng/mL
    Seuil minimal de détection
    0.78 ng/mL
    Application
    ELISA
    Fonction
    Sandwich ELISA for Quantitative Detection of Antigen
    Type d'échantillon
    Cell Culture Lysate, Cell Culture Supernatant, Serum, Tissue Homogenate
    Analytical Method
    Quantitative
    Attributs du produit

    Synonyms: Baculoviral IAP repeat containing 7, Baculoviral IAP repeat containing protein 7, Baculoviral IAP repeat-containing protein 7, BIRC 7, BIRC7, BIRC7_HUMAN, KIAP, Kidney inhibitor of apoptosis protein, LIVIN, Livin inhibitor of apotosis, Melanoma inhibitor of apoptosis protein, ML IAP, ML-IAP, MLIAP, RING finger protein 50, RNF 50, RNF50

    Background: BIRC7, also called KIAP or Livin, is a protein that in humans is encoded by the BIRC7 gene. This gene is mapped to 20q13.33. It encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. BIRC7 blocked apoptosis induced by BAX induction of cytochrome C release from mitochondria, and it also can block apoptosis induced by chemotherapeutic agents.

    Gene Name: BIRC7

    Production: Natural and recombinant human Livin. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: E.coli, Immunogen sequence: M1-S298

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  • Indications d'application

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 50 ng/mL, 25 ng/mL, 12.5 ng/mL, 6.25 ng/mL, 3.12 ng/mL, 1.56 ng/mL, 0.78 ng/mL human Livin standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, cell lysates or tissue homogenates to each empty well. It is recommended that each human Livin standard solution and each sample be measured in duplicate.

    ELISA Dilution: 0.78 ng/mL-50 ng/mL

    Volume d'échantillon
    100 μL
    Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Antigène Voir toutes BIRC7 Kits ELISA
    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
    Autre désignation
    Livin (BIRC7 Produits)
    Synonymes
    KIAP Kit ELISA, LIVIN Kit ELISA, ML-IAP Kit ELISA, MLIAP Kit ELISA, RNF50 Kit ELISA, EIAP/XLX Kit ELISA, XLX Kit ELISA, kiap Kit ELISA, livin Kit ELISA, ml-iap Kit ELISA, mliap Kit ELISA, rnf50 Kit ELISA, xEIAP Kit ELISA, RGD1562883 Kit ELISA, zgc:165605 Kit ELISA, E130019N06 Kit ELISA, Livin Kit ELISA, birc7 Kit ELISA, bird7a Kit ELISA, xEIAP/XLX Kit ELISA, xlx Kit ELISA, EIAP/XLX-B Kit ELISA, birc7b Kit ELISA, baculoviral IAP repeat containing 7 Kit ELISA, baculoviral IAP repeat-containing 7 Kit ELISA, baculoviral IAP repeat-containing 7 (livin) Kit ELISA, baculoviral IAP repeat containing 7 S homeolog Kit ELISA, baculoviral IAP repeat containing 7 L homeolog Kit ELISA, BIRC7 Kit ELISA, birc7 Kit ELISA, Birc7 Kit ELISA, birc7.S Kit ELISA, birc7.L Kit ELISA
    ID gène
    79444
    NCBI Accession
    NP_071444
    UniProt
    Q96CA5
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