MERTK Kit ELISA

N° du produit ABIN6720381

Détail du produit MERTK Kit ELISA

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 156 pg/mL - 10000 pg/mL

Seuil minimal de détection: 156 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Supernatant, Plasma (heparin), Saliva, Serum, Urine

Analytical Method: Quantitative

Attributs du produit:

Synonyms: C mer, c mer proto oncogene tyrosine kinase, MER receptor tyrosine kinase, Mertk, MERTK_HUMAN, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, RP38, STK kinase, Tyrosine-protein kinase Mer

Background: Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. Its gene is mapped to chromosome 2q14.1. Mer encodes a 984-amino acid protein with a calculated molecular mass of 109 kD. It is expressed in numerous neoplastic B- and T-cell lines. Mutations in this gene have been associated with disruption of the retinal pigment epithelium(RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa(RP)

Gene Name: MERTK

Production: Natural and recombinant human Mer. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: sf21, Immunogen sequence: R26-A499

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL human Mer standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin), saliva or urine to each empty well. It is recommended that each human Mer standard solution and each sample be measured in duplicate.

ELISA Dilution: 156pg/mL-10000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Autre désignation: Mer (MERTK Produits)

Synonymes: MER Kit ELISA, RP38 Kit ELISA, c-mer Kit ELISA, Eyk Kit ELISA, Mer Kit ELISA, Nyk Kit ELISA, nmf12 Kit ELISA, rdy Kit ELISA, C-EYK Kit ELISA, MERTK Kit ELISA, DKFZp469D2215 Kit ELISA, si:ch1073-268l12.2 Kit ELISA, MER proto-oncogene, tyrosine kinase Kit ELISA, c-mer proto-oncogene tyrosine kinase Kit ELISA, c-mer proto-oncogene tyrosine kinase a Kit ELISA, MERTK Kit ELISA, Mertk Kit ELISA, mertka Kit ELISA

ID gène: 10461

NCBI Accession: NP_006334

UniProt: Q12866

Pathways: Signalisation RTK