HEV Ab Kit ELISA

N° du produit ABIN997026

Détail du produit HEV Ab Kit ELISA

Antigène: HEV Ab (Hepatitis E Virus Antibody (HEV Ab))

Reactivité: Hepatitis E Virus (HEV)

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: ELISA KIT FOR TOTAL ANTIBODIES TO HEPATITIS E VIRUS Two-Step Incubation, Double Antigen Sandwich Principle

Type d'échantillon: Serum

Analytical Method: Qualitative

Specificité: 99.60%

Sensibilité: 99.80%

Information d'application

Volume d'échantillon: 50 μL

Durée du test: 1 - 2 h

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Date de péremption: 12-18 months

Détail du antigène

Antigène: HEV Ab (Hepatitis E Virus Antibody (HEV Ab))

Autre désignation: HEV Ab (HEV Ab Produits)

Sujet: Hepatitis E virus (HEV) is a non-enveloped, single- stranded RNA virus identified in 1990. Infection with HEV induces acute or sub-clinical liver diseases similar to hepatitis A. HEV infections, endemic and frequently epidemic in developing countries, is seen also in developed countries in a sporadic form with or without a history of traveling to endemic area. The overall case-fatality is 0.5~3%, and much higher (15~25%) among pregnant women. A hypothesis that HEV infection is a zoonosis was presented in 1995. Then a swine HEV and later an avian HEV were identified and sequenced separately in 1997 and 2001. Since then, HEV infection include anti-HEV, viremia and feces excretion of HEV was seen in a wide variety of animals, i.e., swine, rodents, wild monkeys, deer, cow, goats, dogs and chicken in both the developing and developed countries. A direct testimony was reported that the consumption of uncooked dear meat contaminated with HEV led to acute hepatitis E in human, and HEV genome sequences can be detected in pork livers available in the supermarkets in Japan. With the discovery of conformational epitopes in HEV, HEV serology was further explored and understood. The phenomenon of long-lasting and protective antibodies to HEV was observed which greatly enhance the understanding to the diagnosis, epidemiology, zoonosis-related studies and vaccine development.