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KPNA1 Produits

(Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Catégories

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

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Catégories KPNA1 en vedette

KPNA1 Anticorps

High quality antibodies with extensive validation data.

KPNA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KPNA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (6)
N° du produit ABIN3022472
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (5)
N° du produit ABIN561614
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (4)
N° du produit ABIN561613
Quantité 50 μL
Fiche technique Fiche technique

KPNA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6228951
Quantité 96 tests
Fiche technique Fiche technique

KPNA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308914
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7405133
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3093110
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits KPNA1

Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." dans: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

Moriyama, Sangel, Yamaguchi, Obuse, Miyamoto, Oka, Yoneda: "Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box." dans: Biochemical and biophysical research communications, Vol. 462, Issue 3, pp. 201-7, (2015) (PubMed).

Moriyama, Nagai, Oka, Ikawa, Okabe, Yoneda: "Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery." dans: The FEBS journal, Vol. 278, Issue 9, pp. 1561-72, (2011) (PubMed).

Nishimura, Zupunski, Troakes, Kathe, Fratta, Howell, Gallo, Hortobágyi, Shaw, Rogelj: "Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration." dans: Brain : a journal of neurology, Vol. 133, Issue Pt 6, pp. 1763-71, (2010) (PubMed).

Theodore, Kawai, Yang, Kleshchenko, Reddy, Villalta, Arinze: "Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2." dans: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 8984-94, (2008) (PubMed).

Mahalakshmi, Ng, Guo, Qi, Hunziker, Béguin: "Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport." dans: Traffic (Copenhagen, Denmark), Vol. 8, Issue 9, pp. 1164-78, (2007) (PubMed).

Cortes, Ye, Baltimore: "RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 16, pp. 7633-7, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à KPNA1

karyopherin subunit alpha 1 (KPNA1), karyopherin subunit alpha 1 (Kpna1), importin alpha-1 subunit (EHI_124900), karyopherin (importin) alpha 1 (Kpna1), karyopherin alpha 1 (importin alpha 5) (kpna1), AW494490, IPOA5, mSRP1, NPI-1, NPI1, RCH2, Rch2, si:ch211-161h7.7, SRP1

Protein level used designations for KPNA1

  • RAG cohort protein 2
  • SRP1-beta
  • importin alpha 5
  • importin subunit alpha-1
  • importin subunit alpha-5
  • importin-alpha-S1
  • karyopherin subunit alpha-1
  • nucleoprotein interactor 1
  • recombination activating gene cohort 2
  • Importin subunit alpha-1
  • importin alpha-5
  • karyopherin (importin) alpha 1
  • karyopherin/importin alpha-1
  • importin alpha-1 subunit
  • NPI-1
  • importin alpha-S1
  • m-importin-alpha-S1
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