KPNA4 Produits
(Karyopherin (Importin) alpha 4 (KPNA4))
Catégories
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008].
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Catégories KPNA4 en vedette
KPNA4 Anticorps
High quality antibodies with extensive validation data.
KPNA4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KPNA4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (24)
N° du produit
ABIN3015855
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
- (6)
N° du produit
ABIN185160
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7156122
Quantité
100 μg
Fiche technique
Fiche technique
KPNA4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6229027
Quantité
96 tests
Fiche technique
Fiche technique
KPNA4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308922
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7423609
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2724406
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits KPNA4
: "A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration." dans: Brain : a journal of neurology, Vol. 141, Issue 10, pp. 2908-2924, (2019) (PubMed).: "Jietacins, azoxy natural products, as novel NF-κB inhibitors: Discovery, synthesis, biological activity, and mode of action." dans: European journal of medicinal chemistry, Vol. 178, pp. 636-647, (2019) (PubMed).
: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." dans: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).
: "Inhibition of KPNA4 attenuates prostate cancer metastasis." dans: Oncogene, Vol. 36, Issue 20, pp. 2868-2878, (2017) (PubMed).
: "Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation." dans: Journal of cell science, Vol. 128, Issue 12, pp. 2287-301, (2015) (PubMed).
: "Identification of a novel nuclear localization signal of baculovirus late expression factor 11." dans: Virus research, Vol. 184, pp. 111-9, (2014) (PubMed).
: "Cutting edge: tubulin ? functions as an adaptor in NFAT-importin ? interaction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2710-3, (2011) (PubMed).
: "Notch1 signaling is mediated by importins alpha 3, 4, and 7." dans: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 18, pp. 3187-96, (2010) (PubMed).
: "Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication." dans: Journal of virology, Vol. 84, Issue 17, pp. 8650-63, (2010) (PubMed).
: "Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression." dans: Molecular biology of the cell, Vol. 20, Issue 20, pp. 4412-23, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à KPNA4
karyopherin subunit alpha 4 (KPNA4), ARM repeat superfamily protein (MOS6), importin alpha 3 (LOC100533341), karyopherin (importin) alpha 4 (Kpna4), karyopherin subunit alpha 4 (Kpna4), karyopherin alpha 4 (importin alpha 3) S homeolog (kpna4.S), karyopherin alpha 4 (importin alpha 3) (kpna4), 6, 1110058D08Rik, ATIMPALPHA3, IMPA-3, impa3, importin, IMPORTIN ALPHA 3, IMPORTIN ALPHA ISOFORM 3, IPOA3, ipoa3, LOC100224013, MODIFIER OF SNC1, QIP1, qip1, SRP3, srp3, T10M13.16, T10M13_16, wu:fa56d07, wu:fa66g10, wu:fe14c04, wu:fi04h11, wu:fi19b05Protein level used designations for KPNA4
- importin alpha Q1
- importin subunit alpha-3
- importin subunit alpha-4
- karyopherin subunit alpha-4
- importin alpha 3
- karyopherin alpha 4 (importin alpha 3)
- qip1
- karyopherin (importin) alpha 4
- predicted role in nuclear import
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