LECT1 Produits
(Leukocyte Cell Derived Chemotaxin 1 (LECT1))
Catégories
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories LECT1 en vedette
LECT1 Anticorps
High quality antibodies with extensive validation data.
LECT1 Kits ELISA
Reliable ELISA kits for a wide range of species.
LECT1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LECT1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7435004
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN389196
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (2)
N° du produit
ABIN524453
Quantité
100 μL
Fiche technique
Fiche technique
LECT1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957464
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957465
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1140560
Quantité
96 tests
Fiche technique
Fiche technique
LECT1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309288
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396529
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2130329
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits LECT1
: "Chondromodulin-I derived from the inner meniscus prevents endothelial cell proliferation." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 31, Issue 4, pp. 538-43, (2013) (PubMed).: "Cell-specific epigenetic regulation of ChM-I gene expression: crosstalk between DNA methylation and histone acetylation." dans: Biochemical and biophysical research communications, Vol. 365, Issue 1, pp. 124-30, (2007) (PubMed).
: "Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis." dans: Nature medicine, Vol. 12, Issue 10, pp. 1151-9, (2006) (PubMed).
: "Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3." dans: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28789-97, (2004) (PubMed).
: "Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 8542-8548 (PubMed).
Synonymes et noms alternatifs relatifs à LECT1
chondromodulin L homeolog (cnmd.L), leukocyte cell derived chemotaxin 1 (lect1), chondromodulin (CNMD), chondromodulin (cnmd), chondromodulin (Cnmd), bricd3, BRICD3, Bricd3, Chm-1, chm-i, CHM-I, ChM-I, chm1, CHM1, chondromodulin-I, Lect1, MGC53801, MGC82444, MYETS1Protein level used designations for LECT1
- leukocyte cell derived chemotaxin 1
- chondromodulin-I
- chondromodulin-1-like
- chondromodulin-1
- leukocyte cell-derived chemotaxin 1
- BRICHOS domain containing 3
- chondromodulin I
- multiple myeloma tumor suppressor 1
- SCGP
- small cartilage-derived glycoprotein
- Chondromodulin 1
- chM-I
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