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LIFR Produits

(Leukemia Inhibitory Factor Receptor alpha (LIFR))
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5\;8)(p13\;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories LIFR en vedette

LIFR Anticorps

High quality antibodies with extensive validation data.

LIFR Kits ELISA

Reliable ELISA kits for a wide range of species.

LIFR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LIFR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7437698
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7437992
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (8)
N° du produit ABIN7432040
Quantité 100 μL
Fiche technique Fiche technique

LIFR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
N° du produit ABIN6730977
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968279
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957463
Quantité 96 tests
Fiche technique Fiche technique

LIFR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275152
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275153
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN2444162
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LIFR

Worzfeld, Finkernagel, Reinartz, Konzer, Adhikary, Nist, Stiewe, Wagner, Looso, Graumann, Müller: "Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment." dans: Molecular & cellular proteomics : MCP, Vol. 17, Issue 2, pp. 270-289, (2019) (PubMed).

Won, Moreira, Gao, Duttagupta, Zhao, Manuel, Diamond, Yuan, Liu, Jones, DApuzzo, Pal, Kortylewski: "TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs." dans: Journal of leukocyte biology, Vol. 102, Issue 2, pp. 423-436, (2017) (PubMed).

Hammoud, Kirstein, Mournetas, Darracq, Broc, Blanchard, Zeineddine, Mortada, Boeuf: "Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0146281, (2016) (PubMed).

Murphy, Halow, Royer, Hennebold: "Leukemia Inhibitory Factor Is Necessary for Ovulation in Female Rhesus Macaques." dans: Endocrinology, Vol. 157, Issue 11, pp. 4378-4387, (2016) (PubMed).

Reinartz, Finkernagel, Adhikary, Rohnalter, Schumann, Schober, Nockher, Nist, Stiewe, Jansen, Wagner, Müller-Brüsselbach, Müller: "A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome." dans: Genome biology, Vol. 17, Issue 1, pp. 108, (2016) (PubMed).

McIntyre, Alev, Mechael, Salci, Lee, Fiebig-Comyn, Guezguez, Wu, Sheng, Bhatia: "Expansive generation of functional airway epithelium from human embryonic stem cells." dans: Stem cells translational medicine, Vol. 3, Issue 1, pp. 7-17, (2014) (PubMed).

Larsen, Hansen, Møller, Madsen, Scheller, Nielsen, Petersen: "Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer." dans: Molecular and cellular biology, Vol. 30, Issue 17, pp. 4175-87, (2010) (PubMed).

Erices, Conget, Rojas, Minguell: "Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells." dans: Experimental cell research, Vol. 280, Issue 1, pp. 24-32, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à LIFR

leukemia inhibitory factor receptor (Lifr), LIF receptor alpha (LOC397451), LIF receptor alpha (LIFR), LIF receptor alpha (Lifr), leukemia inhibitory factor receptor alpha (LIFR), A230075M04Rik, AW061234, CD118, LIF, LIF-R, SJS2, STWS, SWS

Protein level used designations for LIFR

  • D-factor/LIF receptor
  • LIF receptor
  • LIF-R
  • leukemia inhibitory factor receptor alpha chain
  • soluble differentiation-stimulating factor receptor
  • CD118 antigen
  • leukemia inhibitory factor receptor
  • leukemia inhibitor factor receptor alpha-chain
  • cytokine receptor-beta
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