LIM Domain Binding 3 Produits
(LIM Domain Binding 3 (LDB3))
Catégories
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified\; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010].
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Catégories LIM Domain Binding 3 en vedette
LIM Domain Binding 3 Anticorps
High quality antibodies with extensive validation data.
LIM Domain Binding 3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LIM Domain Binding 3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (2)
- (6)
N° du produit
ABIN524582
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (5)
N° du produit
ABIN7263475
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN6143125
Quantité
100 μL
Fiche technique
Fiche technique
LIM Domain Binding 3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6205510
Quantité
96 tests
Fiche technique
Fiche technique
LIM Domain Binding 3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309259
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3082876
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3130255
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits LIM Domain Binding 3
: "Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy." dans: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13615-26, (2014) (PubMed).: "Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole." dans: Circulation, Vol. 129, Issue 19, pp. 1924-36, (2014) (PubMed).
: "Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked β-N-acetylglucosamine-substituted protein in human heart myofibrils." dans: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4891-8, (2013) (PubMed).
: "Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy." dans: Cardiovascular research, Vol. 83, Issue 1, pp. 80-8, (2009) (PubMed).
: "Mutations in ZASP define a novel form of muscular dystrophy in humans." dans: Annals of neurology, Vol. 57, Issue 2, pp. 269-76, (2005) (PubMed).
: "Characterization and in vivo functional analysis of splice variants of cypher." dans: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7360-5, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à LIM Domain Binding 3
LIM domain binding 3 (LDB3), LIM domain binding 3 (Ldb3), LIM domain binding 3b (ldb3b), LIM domain binding 3 S homeolog (ldb3.S), LIM domain binding 3 (ldb3), LIM domain binding 3a (ldb3a), AW742271, CMD1C, CYPHER, cypher, hm:zehn1639, ldb3, LDB3, ldb3l, LDB3Z1, LDB3Z4, LVNC3, MFM4, MGC52706, MGC75668, ORACLE, PDLIM6, RGD1564875, wu:fi31d08, ZASP, zehn1639, zgc:55814Protein level used designations for LIM Domain Binding 3
- LIM domain-binding protein 3
- PDZ and LIM domain 6
- Z-band alternatively spliced PDZ-motif protein
- protein cypher
- PDZ-LIM domain protein
- cypher
- oracle protein
- protein oracle
- LIM domain binding 3
- LIM domain binding 3 like
- LIM-domain binding factor 3, like
- LIM-domain binding factor 3a
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