Lipin 1 Produits
(Lipin 1 (LPIN1))
Catégories
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012].
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Catégories Lipin 1 en vedette
Lipin 1 Anticorps
High quality antibodies with extensive validation data.
Lipin 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Lipin 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Lipin 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7436306
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7163118
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
IF (cc), IF (p), ELISA, IHC (p), IHC (fro)
Validations
- (2)
N° du produit
ABIN672831
Quantité
100 μL
Fiche technique
Fiche technique
Lipin 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957497
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957498
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957499
Quantité
96 tests
Fiche technique
Fiche technique
Lipin 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309703
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309702
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7398995
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Lipin 1
: "C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis." dans: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10214-29, (2013) (PubMed).: "Expression of cyclins-B and cyclins-e in individual molt-4 cells and in stimulated human-lymphocytes during their progression through the cell-cycle." dans: International journal of oncology, Vol. 3, Issue 6, pp. 1037-42, (2011) (PubMed).
: "Estrogen-related receptor γ (ERRγ) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling." dans: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38035-42, (2011) (PubMed).
: "Subcellular localization and role of lipin-1 in human macrophages." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 6004-13, (2011) (PubMed).
: "Characterization of the human LPIN1-encoded phosphatidate phosphatase isoforms." dans: The Journal of biological chemistry, Vol. 285, Issue 19, pp. 14628-38, (2010) (PubMed).
: "Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism." dans: Human molecular genetics, Vol. 15, Issue 3, pp. 377-86, (2006) (PubMed).
: "Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway." dans: Cell metabolism, Vol. 4, Issue 3, pp. 199-210, (2006) (PubMed).
: "The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme." dans: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9210-8, (2006) (PubMed).
: "Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis." dans: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 32883-9, (2005) (PubMed).
: "Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 1047-52, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à Lipin 1
lipin 1 (LPIN1), lipin 1 (lpin1), phosphatidate phosphatase LPIN1 (LOC100539289), lipin 1 (Lpin1), 4631420P06, fld, Kiaa0188, Lipin1, lipin1, LPIN1, mKIAA0188, pap1, PAP1, zgc:194552, zgc:194558Protein level used designations for Lipin 1
- lipin 1
- phosphatidate phosphatase LPIN1-like
- lipin-1
- phosphatidate phosphatase LPIN1
- fatty liver dystrophy protein
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