LITAF Produits
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Catégories
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008].
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Catégories LITAF en vedette
LITAF Anticorps
High quality antibodies with extensive validation data.
LITAF Kits ELISA
Reliable ELISA kits for a wide range of species.
LITAF Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LITAF recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (4)
N° du produit
ABIN523000
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7158438
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (3)
N° du produit
ABIN7074508
Quantité
100 μL
Fiche technique
Fiche technique
LITAF recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Chicken
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5593872
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1140821
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1140824
Quantité
96 tests
Fiche technique
Fiche technique
LITAF recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123779
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN1098763
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309476
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits LITAF
: "Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes." dans: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1619-37, S1-3, (2013) (PubMed).: "LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 37, pp. 13777-82, (2006) (PubMed).
: "SIMPLE mutations in Charcot-Marie-Tooth disease and the potential role of its protein product in protein degradation." dans: Human mutation, Vol. 25, Issue 4, pp. 372-83, (2005) (PubMed).
: "Mycobacterium bovis Bacillus Calmette-Guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible gene, LITAF(PIG7), and estrogen-inducible gene, EET-1." dans: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 23065-76, (2001) (PubMed).
: "A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor alpha gene expression: molecular cloning, sequencing, characterization, and chromosomal assignment." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4518-23, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à LITAF
lipopolysaccharide induced TNF factor (LITAF), lipopolysaccharide-induced TNF factor (Litaf), LPS-induced TN factor (Litaf), 3222402J11Rik, C85531, EET-1, N4WBP3, PIG7, Pig7, SIMPLE, TBX1, TNF-alpha, TP53I7Protein level used designations for LITAF
- LPS-induced TNF-alpha factor
- lipopolysaccharide-induced TNF-alpha factor
- lipopolysaccharide-induced tumor necrosis factor-alpha factor
- p53-induced gene 7 protein
- small integral membrane protein of lysosome/late endosome
- tumor protein p53 inducible protein 7
- LPS-induced TN factor
- LPS-induced TNF-alpha factor homolog
- estrogen-enhanced transcript protein 1
- estrogen-responsive uterine transcript
- lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
- TNF-alpha factor
- lipid-induced TNF-alpha factor
- tissue necrosis factor-alpha
- LITAF-like protein
- Nedd4 WW domain-binding protein 3
- estrogen-enhanced transcript protein
- mEET
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