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LMO2 Produits

(LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Catégories

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008].

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Catégories LMO2 en vedette

LMO2 Anticorps

High quality antibodies with extensive validation data.

LMO2 Kits ELISA

Reliable ELISA kits for a wide range of species.

LMO2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LMO2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (4)
N° du produit ABIN1098128
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, FACS, StM
Validations
  • (5)
N° du produit ABIN6939966
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application FACS, IF
Validations
  • (3)
N° du produit ABIN6939968
Quantité 100 μg
Fiche technique Fiche technique

LMO2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1155675
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1155676
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1155674
Quantité 96 tests
Fiche technique Fiche technique

LMO2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309514
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3087066
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3133442
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LMO2

Cheng, Ang, A El Farran, Li, Fang, Liu, Kong, Chin, Ling, Lim, Li, Huber, Loh, Loh, Lim: "Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors." dans: Nature communications, Vol. 7, pp. 13396, (2018) (PubMed).

Stanulovic, Cauchy, Assi, Hoogenkamp: "LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage." dans: Nucleic acids research, Vol. 45, Issue 17, pp. 9874-9888, (2017) (PubMed).

Sewell, Tanaka, El Omari, Mancini, Cruz, Fernandez-Fuentes, Chambers, Rabbitts: "Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex." dans: Scientific reports, Vol. 4, pp. 3643, (2014) (PubMed).

Treanor, Zhou, Janke, Churchman, Ma, Lu, Chen, Mullighan, Sorrentino: "Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential." dans: The Journal of experimental medicine, Vol. 211, Issue 4, pp. 701-13, (2014) (PubMed).

Cubedo, Maurin, Jiang, Lossos, Wright: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." dans: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).

Baecklund, Backlin, Mansouri, Klareskog, Askling, Iliadou, Enblad, Lossos, Natkunam, Rosenquist: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." dans: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).

Hirose, Inukai, Kikuchi, Furukawa, Ikawa, Kawamoto, Oram, G��ttgens, Kiyokawa, Miyagawa, Okita, Akahane, Zhang, Kuroda, Honna, Kagami, Goi, Kurosawa, Look, Matsui, Inaba, Sugita: "Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19)." dans: Blood, Vol. 116, Issue 6, pp. 962-70, (2010) (PubMed).

Ryu, Evans-Galea, Gray, Bodine, Persons, Nienhuis: "An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation." dans: Blood, Vol. 111, Issue 4, pp. 1866-75, (2008) (PubMed).

Natkunam, Zhao, Mason, Chen, Taidi, Jones, Hammer, Hamilton Dutoit, Lossos, Levy: "The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas." dans: Blood, Vol. 109, Issue 4, pp. 1636-42, (2007) (PubMed).

Nakayama, Nakayama, Davidson, Sheu, Jinawath, Santillan, Salani, Bristow, Morin, Kurman, Wang, Shih: "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18739-44, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à LMO2

LIM domain only 2 (lmo2), LIM domain only 2 (LMO2), LIM domain only 2 (Lmo2), LIM domain only 2 (rhombotin-like 1) (lmo2), LIM domain only 2 S homeolog (lmo2.S), LMO-2, lmo2-A, Rbtn-2, Rbtn2, RBTN2, RBTNL1, Rhom-2, RHOM2, rhombotin-2, Ttg2, TTG2, wu:fc83a08, xlmo2, zgc:111930

Protein level used designations for LMO2

  • Rhombotin-2
  • LIM domain only 2 (rhombotin-like 1)
  • LIM domain only protein 2
  • LIM only 2
  • LMO-2
  • T-cell translocation protein 2
  • cysteine-rich protein TTG-2
  • rhombotin-2
  • T-cell translocation gene 2
  • rhombotin 2
  • rhombotin-like 1
  • LIM domain only-2
  • ttg2
  • zlmo2
  • xLMO-2
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