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LMTK2 Produits

(Lemur tyrosine Kinase 2 (LMTK2))
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009].

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Catégories LMTK2 en vedette

LMTK2 Anticorps

High quality antibodies with extensive validation data.

LMTK2 Kits ELISA

Reliable ELISA kits for a wide range of species.

LMTK2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LMTK2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6258874
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
N° du produit ABIN524806
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN391208
Quantité 400 μL
Fiche technique Fiche technique

LMTK2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648270
Quantité 96 tests
Fiche technique Fiche technique

LMTK2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309527
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3134993
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LMTK2

Shah, Bradbury: "Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy." dans: Oncotarget, Vol. 6, Issue 16, pp. 14233-46, (2015) (PubMed).

Zheng, Hsing, Sun, Chu, Yu, Li, Gao, Kim, Isaacs, Shen, Gao, Hoover, Xu: "Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men." dans: The Prostate, Vol. 70, Issue 4, pp. 425-32, (2010) (PubMed).

Kawa, Fujimoto, Tezuka, Nakazawa, Yamamoto: "Involvement of BREK, a serine/threonine kinase enriched in brain, in NGF signalling." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 9, Issue 3, pp. 219-32, (2004) (PubMed).

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." dans: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." dans: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à LMTK2

lemur tyrosine kinase 2 (LMTK2), lemur tyrosine kinase 2 (Lmtk2), 2900041G10Rik, A330101P12Rik, AATYK2, aatyk2, BREK, cprk, KPI-2, KPI2, LMR2

Protein level used designations for LMTK2

  • CDK5/p35-regulated kinase
  • apoptosis-associated tyrosine kinase 2
  • brain-enriched kinase
  • cyclin-dependent kinase 5/p35-regulated kinase
  • hBREK
  • kinase phosphatase inhibitor 2
  • kinase/phosphatase/inhibitor 2
  • serine/threonine-protein kinase KPI-2
  • serine/threonine-protein kinase LMTK2
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