Low Density Lipoprotein Receptor Produits
(Low Density Lipoprotein Receptor (LDLR))
Catégories
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
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Catégories Low Density Lipoprotein Receptor en vedette
Low Density Lipoprotein Receptor Anticorps
High quality antibodies with extensive validation data.
Low Density Lipoprotein Receptor Kits ELISA
Reliable ELISA kits for a wide range of species.
Low Density Lipoprotein Receptor Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Low Density Lipoprotein Receptor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, FACS, IHC
Validations
- (5)
N° du produit
ABIN5542334
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN7268296
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Hamster, Human, Mouse, Plant, Rat
Application
WB, ELISA, FACS, IF (p), IHC (p)
Validations
- (5)
- (3)
N° du produit
ABIN672111
Quantité
100 μL
Fiche technique
Fiche technique
Low Density Lipoprotein Receptor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957532
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968344
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968345
Quantité
96 tests
Fiche technique
Fiche technique
Low Density Lipoprotein Receptor recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275138
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275139
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1309277
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Low Density Lipoprotein Receptor
: "VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content." dans: EMBO reports, Vol. 21, Issue 7, pp. e49343, (2020) (PubMed).: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." dans: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).
: "Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 188-199, (2019) (PubMed).
: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).
: "Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells." dans: Scientific reports, Vol. 9, Issue 1, pp. 6650, (2019) (PubMed).
: "Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr-/-mice." dans: Scientific reports, Vol. 7, Issue 1, pp. 17845, (2018) (PubMed).
: "The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins." dans: Molecular metabolism, Vol. 16, pp. 88-99, (2018) (PubMed).
: "Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex." dans: Scientific reports, Vol. 8, Issue 1, pp. 16845, (2018) (PubMed).
: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" dans: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).
: "27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells." dans: Neurotoxicology, Vol. 59, pp. 88-97, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à Low Density Lipoprotein Receptor
low density lipoprotein receptor (LDLR), low density lipoprotein receptor (Ldlr), low density lipoprotein receptor a (ldlra), low density lipoprotein receptor S homeolog (ldlr.S), low density lipoprotein receptor L homeolog (ldlr.L), FH, FHC, fhc, Hlb301, LDLA, LDLCQ2, ldlcq2, ldlr, ldlr-a, ldlr-b, ldlr2-a, LDLRA, LDL receptor-2, LDL receptor 1Protein level used designations for Low Density Lipoprotein Receptor
- LDL receptor
- low-density lipoprotein receptor
- low-density lipoprotein receptor class A domain-containing protein 3
- low density lipoprotein receptor (familial hypercholesterolemia)
- LDL receptor 2
- low density lipoprotein receptor-2
- low-density lipoprotein receptor 2
- LDL receptor-1
- low-density lipoprotein receptor 1
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