LOX Produits
(Lysyl Oxidase (LOX))
Catégories
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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Catégories LOX en vedette
LOX Anticorps
High quality antibodies with extensive validation data.
LOX Kits ELISA
Reliable ELISA kits for a wide range of species.
LOX Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LOX recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (7)
N° du produit
ABIN7435016
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Rat
Application
WB, IHC, FACS, IF, IHC (p)
Validations
- (7)
N° du produit
ABIN1491218
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP
Validations
- (4)
N° du produit
ABIN7268347
Quantité
100 μL
Fiche technique
Fiche technique
LOX recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
N° du produit
ABIN6957599
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6957600
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6957601
Quantité
96 tests
Fiche technique
Fiche technique
LOX recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (12)
- (1)
N° du produit
ABIN2712316
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123817
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413259
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits LOX
: "Eliminating Regurgitation Reduces Fibrotic Remodeling of Functional Mitral Regurgitation Conditioned Valves." dans: Annals of biomedical engineering, Vol. 46, Issue 5, pp. 670-683, (2019) (PubMed).: "LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy." dans: Oncogene, Vol. 37, Issue 36, pp. 4921-4940, (2019) (PubMed).
: "TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro." dans: Connective tissue research, Vol. 60, Issue 5, pp. 495-506, (2019) (PubMed).
: "Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia." dans: Experimental & molecular medicine, Vol. 51, Issue 2, pp. 20, (2019) (PubMed).
: "Lysyl oxidase-a possible role in systemic sclerosis-associated pulmonary hypertension: a multicentre study. ..." dans: Rheumatology (Oxford, England), (2019) (PubMed).
: "LOX and ACSL5 as potential relapse markers for pancreatic cancer patients." dans: Cancer biology & therapy, Vol. 20, Issue 6, pp. 787-798, (2019) (PubMed).
: "Decreased lysyl oxidase level protects against development of retinal vascular lesions in diabetic retinopathy." dans: Experimental eye research, Vol. 184, pp. 221-226, (2019) (PubMed).
: "Cyclophilin B control of lysine post-translational modifications of skin type I collagen." dans: PLoS genetics, Vol. 15, Issue 6, pp. e1008196, (2019) (PubMed).
: "Type III collagen is a key regulator of the collagen fibrillar structure and biomechanics of articular cartilage and meniscus." dans: Matrix biology : journal of the International Society for Matrix Biology, (2019) (PubMed).
: "Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness." dans: Thyroid : official journal of the American Thyroid Association, Vol. 29, Issue 1, pp. 79-92, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à LOX
lysyl oxidase (LOX), lysyl oxidase (lox), lysyl oxidase a (loxa), lysyl oxidase L homeolog (lox.L), lysyl oxidase (Lox), AI893619, H-rev142, LOX, lox, MGC146507, Rrg1, TSC-160, Xlox, zgc:77447Protein level used designations for LOX
- lysyl oxidase
- protein-lysine 6-oxidase-like
- protein-lysine 6-oxidase
- ras excision protein
- ras recision gene (rrg)
- Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts)
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