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LOXL2 Produits

(Lysyl Oxidase-Like 2 (LOXL2))
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008].

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Catégories LOXL2 en vedette

LOXL2 Anticorps

High quality antibodies with extensive validation data.

LOXL2 Kits ELISA

Reliable ELISA kits for a wide range of species.

LOXL2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LOXL2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC, IHC (p), IF
Validations
  • (5)
  • (8)
N° du produit ABIN2856034
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7438565
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (5)
N° du produit ABIN7127602
Quantité 100 μL
Fiche technique Fiche technique

LOXL2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6975613
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN6957604
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957605
Quantité 96 tests
Fiche technique Fiche technique

LOXL2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309674
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
N° du produit ABIN7504457
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398506
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LOXL2

Cebrià-Costa, Pascual-Reguant, Gonzalez-Perez, Serra-Bardenys, Querol, Cosín, Verde, Cigliano, Sanseverino, Segura-Bayona, Iturbide, Andreu, Nuciforo, Bernado-Morales, Rodilla, Arribas, Yelamos et al.: "LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells. ..." dans: Oncogene, Vol. 39, Issue 1, pp. 79-121, (2020) (PubMed).

Cao, Lin, Zhi, Lazare, Meng, Wu, Gao, Wei, Wu: "LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype." dans: Frontiers in oncology, Vol. 10, pp. 284, (2020) (PubMed).

Sanada, Islam, Kaminota, Kirino, Tanimoto, Yoshimitsu, Yano, Mizuno, Okada, Mitani, Ugumori, Tanaka, Hato: "Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma." dans: The Laryngoscope, Vol. 130, Issue 5, pp. E327-E334, (2020) (PubMed).

Mahjour, Dambal, Shrestha, Singh, Noonan, Kantarci, Trackman: "Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB." dans: Oncogenesis, Vol. 8, Issue 5, pp. 34, (2019) (PubMed).

Tjin, White, Faiz, Sicard, Tschumperlin, Mahar, Kable, Burgess: "Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis." dans: Disease models & mechanisms, Vol. 10, Issue 11, pp. 1301-1312, (2018) (PubMed).

Fu, Bai, Liu, Zhou, Zheng: "The serum level and significance of lysyl oxidase-like 2 in patients with rheumatoid arthritis-associated interstitial lung disease." dans: Clinical rheumatology, Vol. 37, Issue 1, pp. 193-198, (2018) (PubMed).

Jeong, Park, Mun, Kwak, Lee, Oh: "Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer." dans: Oncology letters, Vol. 15, Issue 2, pp. 2431-2440, (2018) (PubMed).

Park, Lee, Lee, Kim, Dong, Yoon: "Emerging role of LOXL2 in the promotion of pancreas cancer metastasis." dans: Oncotarget, Vol. 7, Issue 27, pp. 42539-42552, (2018) (PubMed).

Cuevas, Eraso, Mazón, Santos, Moreno-Bueno, Cano, Portillo: "LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway." dans: Scientific reports, Vol. 7, pp. 44988, (2018) (PubMed).

Wang, Zhao, Zhu, Liu, Liang, Liu, Zhang, Dong, Sun: "HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 60, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à LOXL2

lysyl oxidase like 2 (LOXL2), lysyl oxidase-like 2 (lox2), lysyl oxidase-like 2 (Loxl2), lysyl oxidase homolog 4 (LOC408544), lysyl oxidase-like 2 (LOXL2), lysyl oxidase like 2 L homeolog (loxl2.L), lysyl oxidase like 2 (loxl2), lysyl oxidase like 2 (Loxl2), lysyl oxidase-like 2b (loxl2b), 1110004B06Rik, 4930526G11Rik, 9430067E15Rik, CG4402, Dmel\\CG4402, dmlox-2, Dmloxl-2, GB13360, im:7136137, LOR2, lor2, lox2-like, loxl-2, LOXL2, si:dkeyp-32b1.1, WS9-14, ws9-14, wu:fk12g04, zgc:158414

Protein level used designations for LOXL2

  • lysyl oxidase homolog 2
  • lysyl oxidase related 2
  • lysyl oxidase-like protein 2
  • lysyl oxidase-related protein 2
  • lysyl oxidase-related protein WS9-14
  • CG4402-PA
  • lox2-PA
  • lysyl oxidase-like 2
  • Lysyl oxidase-like protein 2
  • lysyl oxidase homolog 2-like
  • Lysyl oxidase homolog 2
  • Lysyl oxidase-like protein 2B
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