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CD160 (human): 293T Lysate

CD160 WB Whole Cell Lysate Overexpression Lysate HEK 293T Cells
N° du produit ABIN1112255
  • Antigène Tous les produits CD160
    CD160
    Espèce du lysat
    Human Cells
    Application
    Western Blotting (WB)
    Attributs du produit
    CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol- anchored protein of 181 amino acids with a single Ig- like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. Lysate of human CD160 transfected 293T cells
    Lysed Cells
    HEK 293T Cells
    Lysate Type
    Overexpression Lysate
    Lysate Fraction
    Whole Cell Lysate
  • Indications d'application
    CD160 (h): 293T Lysate is suitable as a Western Blotting positive control for human reactive CD160 antibodies. Recommended use: 10-20 µl per lane. Control 293T Lysate: 293LYS is available as a Western Blotting negative control lysate derived from non-transfected 293T cells.
    Restrictions
    For Research Use only
  • Conseil sur la manipulation
    Repeated freezing and thawing should be minimized. Sample vial should be boiled once prior to use. Non-hazardous. No MSDS required.
    Stock
    -20 °C
  • Edwards, Durant, Jones, Evans, Smith: "Differential expression of HLA class II antigens in fetal human spleen: relationship of HLA-DP, DQ, and DR to immunoglobulin expression." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 137, Issue 2, pp. 490-7, (1986) (PubMed).

    Austin, Trowsdale, Rudd, Bodmer, Feldmann, Lamb: "Functional expression of HLA-DP genes transfected into mouse fibroblasts." dans: Nature, Vol. 313, Issue 5997, pp. 61-4, (1985) (PubMed).

    Royston, Omary, Trowbridge: "Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia." dans: Transplantation proceedings, Vol. 13, Issue 1 Pt 2, pp. 761-6, (1981) (PubMed).

  • Antigène
    CD160
    Autre désignation
    CD160 (CD160 Produits)
    Synonymes
    CD160 Lysate, RGD1563598 Lysate, BY55 Lysate, AU045688 Lysate, By55 Lysate, NK1 Lysate, NK28 Lysate, CD160 molecule Lysate, CD160 antigen Lysate, CD160 Lysate, Cd160 Lysate
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