Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MACC1 Produits

(Metastasis Associated in Colon Cancer 1 (MACC1))
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories MACC1 en vedette

MACC1 Anticorps

High quality antibodies with extensive validation data.

MACC1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MACC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MACC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (6)
  • (5)
N° du produit ABIN706526
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7159558
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
N° du produit ABIN1859735
Quantité 100 μL
Fiche technique Fiche technique

MACC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957784
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975740
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5656849
Quantité 96 tests
Fiche technique Fiche technique

MACC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7386299
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3093653
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3010685
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MACC1

Shi, Song, Wang, Zhang, Zheng: "MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).

Montorsi, Guizzetti, Alecci, Caporali, Martello, Atene, Parenti, Pizzini, Zanovello, Bortoluzzi, Ferrari, Grande, Zanocco-Marani: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." dans: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).

Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: "A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway." dans: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 76, (2016) (PubMed).

Sun, Li, Dai, Tan, Zhao, Li, Wang: "Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells." dans: Molecular medicine reports, Vol. 12, Issue 3, pp. 3423-31, (2015) (PubMed).

Ge, Meng, Zhou, Zhang, Ding: "Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 1094-100, (2015) (PubMed).

Koelzer, Herrmann, Zlobec, Karamitopoulou, Lugli, Stein: "Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study." dans: BMC cancer, Vol. 15, pp. 160, (2015) (PubMed).

Li, Zhang, Zhao, Shi, Yao, Zhang, Guo, Liu: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." dans: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).

Kuo, Wu, Chang, Huang, Lin, Yan, Sheu, Lu, Chang, Lai, Wang: "Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression." dans: International journal of cancer, Vol. 135, Issue 3, pp. 563-73, (2014) (PubMed).

Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: "Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis." dans: Neuro-oncology, Vol. 15, Issue 12, pp. 1696-709, (2013) (PubMed).

Guo, Yang, Yao, Zhang, Da, Duan: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." dans: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à MACC1

MACC1, MET transcriptional regulator (MACC1), metastasis associated in colon cancer 1 (Macc1), MACC1, MET transcriptional regulator (Macc1), 7A5, 7a5, 4732474O15Rik, Gm267, RGD1309838, SH3BP4L

Protein level used designations for MACC1

  • SH3 domain-containing protein 7a5
  • metastasis-associated in colon cancer protein 1
  • putative binding protein 7a5
Vous êtes ici:
Support technique