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MAPK7 Produits

(Mitogen-Activated Protein Kinase 7 (MAPK7))

Catégories

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Catégories MAPK7 en vedette

MAPK7 Anticorps

High quality antibodies with extensive validation data.

MAPK7 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MAPK7 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN3022945
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7442186
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (5)
N° du produit ABIN3031834
Quantité 0.4 mL
Fiche technique Fiche technique

MAPK7 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6216856
Quantité 96 tests
Fiche technique Fiche technique

MAPK7 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310301
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310300
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5508923
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MAPK7

Zhuang, Zhang, Xiong, Wang, Luo, Han, Meng, Zhang, Liao, Liu: "CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis." dans: Cell death & disease, Vol. 7, Issue 10, pp. e2415, (2017) (PubMed).

Sawhney, Liu, Brattain: "A novel role of ERK5 in integrin-mediated cell adhesion and motility in cancer cells via Fak signaling." dans: Journal of cellular physiology, Vol. 219, Issue 1, pp. 152-61, (2009) (PubMed).

Zhao, Geng, Ge, Wang, Zhang, Kang: "Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells." dans: Molecular and cellular biochemistry, Vol. 322, Issue 1-2, pp. 171-8, (2009) (PubMed).

Montero, Ocaña, Abad, Ortiz-Ruiz, Pandiella, Esparís-Ogando: "Expression of Erk5 in early stage breast cancer and association with disease free survival identifies this kinase as a potential therapeutic target." dans: PLoS ONE, Vol. 4, Issue 5, pp. e5565, (2009) (PubMed).

Zen, Yasui, Nakajima, Zen, Zen, Gen, Mitsuyoshi, Minami, Mitsufuji, Tanaka, Itoh, Nakanuma, Taniwaki, Arii, Okanoue, Yoshikawa: "ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry." dans: Genes, chromosomes & cancer, Vol. 48, Issue 2, pp. 109-20, (2008) (PubMed).

Arnoux, Nassour, LHelgoualch, Hipskind, Savagner: "Erk5 controls Slug expression and keratinocyte activation during wound healing." dans: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4738-49, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à MAPK7

mitogen-activated protein kinase 7 (MAPK7), mitogen-activated protein kinase 7 (Mapk7), MAP kinase 7 (MPK7), mitogen-activated protein kinase 7 L homeolog (mapk7.L), ATMPK7, BMK1, Bmk1, bmk1, ERK-5, ERK4, erk4, ERK5, Erk5, Erk5-T, F8D23.5, F8D23_5, mapk7, MAP kinase 7, PRKM7, Prkm7, prkm7

Protein level used designations for MAPK7

  • BMK-1
  • BMK1 kinase
  • ERK-5
  • MAP kinase 7
  • MAPK 7
  • big MAP kinase 1
  • extracellular signal-regulated kinase 5
  • extracellular-signal-regulated kinase 5
  • extracellular signal regulated kinase 5
  • mitogen activated protein kinase 7
  • mitogen-activated kinase 7
  • Big MAP kinase 1
  • Extracellular signal-regulated kinase 5
  • LOW QUALITY PROTEIN: mitogen-activated protein kinase 7
  • ERK5
  • bmk I
  • mitogen-activated protein kinase 7 L homeolog
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