MAPK8IP1 Produits
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Catégories
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011].
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Catégories MAPK8IP1 en vedette
MAPK8IP1 Anticorps
High quality antibodies with extensive validation data.
MAPK8IP1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MAPK8IP1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN652961
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN2854806
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC
Validations
- (2)
N° du produit
ABIN3185263
Quantité
100 μL
Fiche technique
Fiche technique
MAPK8IP1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6227128
Quantité
96 tests
Fiche technique
Fiche technique
MAPK8IP1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3093174
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3137545
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2725443
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MAPK8IP1
: "Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons." dans: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 35113-8, (2000) (PubMed).: "IB1, a JIP-1-related nuclear protein present in insulin-secreting cells." dans: The Journal of biological chemistry, Vol. 273, Issue 4, pp. 1843-6, (1998) (PubMed).
: "A cytoplasmic inhibitor of the JNK signal transduction pathway." dans: Science (New York, N.Y.), Vol. 277, Issue 5326, pp. 693-6, (1997) (PubMed).
Synonymes et noms alternatifs relatifs à MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mitogen-activated protein kinase 8 interacting protein 1 (Mapk8ip1), IB1, JIP-1, Jip-1, Jip1, JIP1, Mapk8ip, mjip-2a, Prkm8ip, PRKM8IP, SkipProtein level used designations for MAPK8IP1
- mitogen-activated protein kinase 8 interacting protein 1
- c-Jun-amino-terminal kinase-interacting protein 1-like
- C-Jun-amino-terminal kinase-interacting protein 1
- IB-1
- JNK MAP kinase scaffold protein 1
- JNK-interacting protein 1
- islet-brain-1
- mitogen activated protein kinase 8 interacting protein 1
- mitogen-activated protein kinase 8-interacting protein 1
- protein kinase, mitogen-activated 8 interacting protein
- JIP-1-related protein
- JRP
- mitogen activated protein kinase 8 interacting protein
- PRKM8 interacting protein
- islet-brain 1
- islet brain 1
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