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MAPKAP Kinase 2 Produits

(Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Catégories

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories MAPKAP Kinase 2 en vedette

MAPKAP Kinase 2 Anticorps

High quality antibodies with extensive validation data.

MAPKAP Kinase 2 Kits ELISA

Reliable ELISA kits for a wide range of species.

MAPKAP Kinase 2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MAPKAP Kinase 2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7441769
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IP, IF, PLA
Validations
  • (8)
N° du produit ABIN563999
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (5)
N° du produit ABIN522742
Quantité 100 μg
Fiche technique Fiche technique

MAPKAP Kinase 2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968658
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380843
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380304
Quantité 2 x 96 tests
Fiche technique Fiche technique

MAPKAP Kinase 2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310322
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310324
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5508995
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MAPKAP Kinase 2

Xu, Zhou, Xiong, Zou, Deng, Ganaie, Kleiboeker, Peng, Liu, Wang, Ye, Qiu: "Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway." dans: PLoS pathogens, Vol. 13, Issue 3, pp. e1006266, (2017) (PubMed).

Rosenzweig, Ou, Quinn: "P38 mitogen-activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture." dans: Journal of cellular and molecular medicine, Vol. 17, Issue 4, pp. 508-17, (2013) (PubMed).

Rosenzweig, Djap, Ou, Quinn: "Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis." dans: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 12, pp. 1591-602, (2012) (PubMed).

Concejero, Chen, Wang, Wang, Lin, Liu, Yang, Yong, Lin, Jawan, Huang, Cheng, Eng: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." dans: Transplantation, Vol. 85, Issue 3, pp. 398-406, (2008) (PubMed).

Manke, Nguyen, Lim, Stewart, Elia, Yaffe: "MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation." dans: Molecular cell, Vol. 17, Issue 1, pp. 37-48, (2005) (PubMed).

Lukas, Kroe, Wildeson, Peet, Frego, Davidson, Ingraham, Pargellis, Labadia, Werneburg: "Catalysis and function of the p38 alpha.MK2a signaling complex." dans: Biochemistry, Vol. 43, Issue 31, pp. 9950-60, (2004) (PubMed).

Cheng, Tseng, Chang, Chang, Lai: "Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2." dans: Journal of cellular biochemistry, Vol. 89, Issue 3, pp. 589-602, (2003) (PubMed).

Underwood, Parris, Federico, Mosyak, Czerwinski, Shane, Taylor, Svenson, Liu, Hsiao, Wolfrom, Maguire, Malakian, Telliez, Lin, Kriz, Seehra, Somers, Stahl: "Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme." dans: Structure (London, England : 1993), Vol. 11, Issue 6, pp. 627-36, (2003) (PubMed).

Meng, Swenson, Fitzgibbon, Hayakawa, Ter Haar, Behrens, Fulghum, Lippke: "Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export." dans: The Journal of biological chemistry, Vol. 277, Issue 40, pp. 37401-5, (2002) (PubMed).

Han, Leng, Bian, Mahanivong, Carpenter, Pan, Han, Huang: "Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells." dans: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48379-85, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à MAPKAP Kinase 2

mitogen-activated protein kinase-activated protein kinase 2a (mapkapk2a), mitogen-activated protein kinase-activated protein kinase 2 L homeolog (mapkapk2.L), mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), MAP kinase-activated protein kinase 2 (Mapkapk2), mitogen-activated protein kinase-activated protein kinase 2 (Mapkapk2), AA960234, MAPKAP-K2, mapkapk2, MAPKAPK2, MGC78852, MK-2, MK2, Rps6kc1, wu:fb30e10, wu:fc56c10, wu:fi03a01

Protein level used designations for MAPKAP Kinase 2

  • MAP kinase-activated protein kinase 2
  • bbp
  • betty boop
  • mitogen-activated protein kinase-activated protein kinase 2
  • MAPK-activated protein kinase 2
  • MAPKAP kinase 2
  • MAPKAPK-2
  • map kinase activated protein kinase-2
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