MAPKAP Kinase 5 Produits
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
Catégories
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012].
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Catégories MAPKAP Kinase 5 en vedette
MAPKAP Kinase 5 Anticorps
High quality antibodies with extensive validation data.
MAPKAP Kinase 5 Kits ELISA
Reliable ELISA kits for a wide range of species.
MAPKAP Kinase 5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MAPKAP Kinase 5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
N° du produit
ABIN710546
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN389587
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
- (2)
N° du produit
ABIN969362
Quantité
100 μL
Fiche technique
Fiche technique
MAPKAP Kinase 5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380844
Quantité
2 x 96 tests
Fiche technique
Fiche technique
MAPKAP Kinase 5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
N° du produit
ABIN1310330
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310332
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7317049
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MAPKAP Kinase 5
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition." dans: Toxicon : official journal of the International Society on Toxinology, Vol. 55, Issue 4, pp. 827-37, (2010) (PubMed).
: "Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs." dans: Science signaling, Vol. 2, Issue 94, pp. ra69, (2009) (PubMed).
: "PRAK is essential for ras-induced senescence and tumor suppression." dans: Cell, Vol. 128, Issue 2, pp. 295-308, (2007) (PubMed).
: "p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development." dans: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 97, Issue 8, pp. 629-40, (2005) (PubMed).
: "Effect of different dietary ideal protein concentrations on broiler performance." dans: British poultry science, Vol. 45, Issue 4, pp. 504-11, (2004) (PubMed).
: "Regulation of PRAK subcellular location by p38 MAP kinases." dans: Molecular biology of the cell, Vol. 14, Issue 6, pp. 2603-16, (2003) (PubMed).
: "p62 functions as a p38 MAP kinase regulator." dans: Biochemical and biophysical research communications, Vol. 269, Issue 2, pp. 521-5, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à MAPKAP Kinase 5
mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5), MAP kinase-activated protein kinase 5 (Mapkapk5), mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5), MAPKAP-K5, MAPKAPK5, MK-5, MK5, PRAKProtein level used designations for MAPKAP Kinase 5
- mitogen-activated protein kinase-activated protein kinase 5
- MAP kinase-activated protein kinase 5
- MAP kinase-activated protein kinase 5-like
- MAPK-activated protein kinase 5
- MAPKAP kinase 5
- MAPKAPK-5
- p38-regulated/activated protein kinase
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