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MARK2 Produits

(MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Catégories

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009].

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Catégories MARK2 en vedette

MARK2 Anticorps

High quality antibodies with extensive validation data.

MARK2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MARK2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (5)
N° du produit ABIN560734
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN392538
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application ELISA, WB, IHC
Validations
  • (5)
N° du produit ABIN3031689
Quantité 0.4 mL
Fiche technique Fiche technique

MARK2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6219503
Quantité 96 tests
Fiche technique Fiche technique

MARK2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310392
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310391
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5508999
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MARK2

Parker, Krantz, Kwak, Barker, Deer, Lee, Mouneimne, Langlais: "Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-end Tracking Protein Network in Adipocytes." dans: Molecular & cellular proteomics : MCP, Vol. 18, Issue 7, pp. 1363-1381, (2019) (PubMed).

Kruse, Krantz, Barker, Coletta, Rafikov, Luo, Højlund, Mandarino, Langlais: "Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein." dans: Molecular & cellular proteomics : MCP, Vol. 16, Issue 10, pp. 1718-1735, (2017) (PubMed).

Yoshiike, Yamashita, Mizoroki, Maeda, Murayama, Kimura, Sahara, Soeda, Takashima: "Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes." dans: Aging cell, Vol. 11, Issue 1, pp. 51-62, (2012) (PubMed).

Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: "Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms." dans: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2414-25, (2008) (PubMed).

Depasquale, Thompson: "Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF." dans: Histopathology, Vol. 52, Issue 4, pp. 500-9, (2008) (PubMed).

Hurov, Watkins, Piwnica-Worms: "Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity." dans: Current biology : CB, Vol. 14, Issue 8, pp. 736-41, (2004) (PubMed).

Hueso, Beltran, Moreso, Ciriero, Fulladosa, Grinyó, Serón, Navarro et al.: "Splicing alterations in human renal allografts: detection of a new splice variant of protein kinase Par1/Emk1 whose expression is associated with an increase of inflammation in protocol biopsies of ..." dans: Biochimica et biophysica acta, Vol. 1689, Issue 1, pp. 58-65, (2004) (PubMed).

Cantrell: "Phosphoinositide 3-kinase signalling pathways." dans: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." dans: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).

Sun, Lu, Feng, Reinhard, Jan, Fantl, Williams: "PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling." dans: Nature cell biology, Vol. 3, Issue 7, pp. 628-36, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à MARK2

microtubule affinity regulating kinase 2 (MARK2), MAP/microtubule affinity regulating kinase 2 (Mark2), microtubule affinity regulating kinase 2 (Mark2), AU024026, Emk, EMK-1, EMK1, mKIAA4207, PAR-1, Par-1, Par-1b, Par1b

Protein level used designations for MARK2

  • ELKL motif kinase 1
  • PAR1 homolog b
  • Ser/Thr protein kinase PAR-1B
  • serine/threonine protein kinase EMK
  • serine/threonine-protein kinase MARK2
  • EMK-1
  • EMK1
  • serine/threonine kinase
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