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MATK Produits

(Megakaryocyte-Associated tyrosine Kinase (MATK))
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories MATK en vedette

MATK Anticorps

High quality antibodies with extensive validation data.

MATK Kits ELISA

Reliable ELISA kits for a wide range of species.

MATK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MATK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7159178
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (1)
  • (2)
N° du produit ABIN969495
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, ICC, IF
Validations
  • (3)
N° du produit ABIN6259101
Quantité 100 μL
Fiche technique Fiche technique

MATK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN4886198
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5594938
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1141899
Quantité 96 tests
Fiche technique Fiche technique

MATK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310443
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310445
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509002
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MATK

McShan, Zagozdzon, Park, Zrihan-Licht, Fu, Avraham, Avraham: "Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." dans: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).

Zagozdzon, Bougeret, Fu, Avraham: "Overexpression of the Csk homologous kinase facilitates phosphorylation of Akt/PKB in MCF-7 cells." dans: International journal of oncology, Vol. 21, Issue 6, pp. 1347-52, (2002) (PubMed).

Kim, Zagozdzon, Meisler, Baleja, Fu, Avraham, Avraham: "Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer." dans: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36465-70, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à MATK

megakaryocyte-associated tyrosine kinase (matk), megakaryocyte-associated tyrosine kinase (MATK), megakaryocyte-associated tyrosine kinase (Matk), zinc finger RNA binding protein 2 (ZFR2), Batk, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk, Ntk, si:ch211-63j24.2

Protein level used designations for MATK

  • megakaryocyte-associated tyrosine kinase
  • megakaryocyte-associated tyrosine-protein kinase-like
  • CSK homologous kinase
  • Csk-homologous kinase
  • Csk-type protein tyrosine kinase
  • HYL tyrosine kinase
  • hematopoietic consensus tyrosine-lacking kinase
  • hydroxyaryl-protein kinase
  • leukocyte carboxyl-terminal src kinase related
  • megakaryocyte-associated tyrosine-protein kinase
  • protein kinase HYL
  • tyrosine kinase MATK
  • tyrosine-protein kinase CTK
  • tyrosylprotein kinase
  • Csk homologous kinase
  • protein kinase NTK
  • megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase)
  • non-receptor protein kinase protein
  • protein kinase BATK
  • carboxyl-terminal SRC kinase homologous kinase
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