MAX Produits
(MYC Associated Factor X (MAX))
Catégories
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Catégories MAX en vedette
MAX Anticorps
High quality antibodies with extensive validation data.
MAX Kits ELISA
Reliable ELISA kits for a wide range of species.
MAX Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MAX recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (4)
N° du produit
ABIN561745
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN184586
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7165797
Quantité
100 μg
Fiche technique
Fiche technique
MAX recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968708
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957925
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951174
Quantité
96 tests
Fiche technique
Fiche technique
MAX recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN666983
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310452
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN1097137
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MAX
: "lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer." dans: Cancer cell, Vol. 33, Issue 4, pp. 706-720.e9, (2019) (PubMed).: "Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus." dans: European journal of immunology, Vol. 46, Issue 1, pp. 167-77, (2016) (PubMed).
: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." dans: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).
: "Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X." dans: International journal of cancer, Vol. 135, Issue 9, pp. 2054-64, (2014) (PubMed).
: "Max is acetylated by p300 at several nuclear localization residues." dans: The Biochemical journal, Vol. 403, Issue 3, pp. 397-407, (2007) (PubMed).
: "HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity." dans: Cancer cell, Vol. 11, Issue 4, pp. 335-47, (2007) (PubMed).
: "SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes." dans: Molecular cell, Vol. 24, Issue 5, pp. 771-83, (2006) (PubMed).
: "Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc." dans: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32994-9, (2003) (PubMed).
: "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc." dans: Science (New York, N.Y.), Vol. 251, Issue 4998, pp. 1211-7, (1991) (PubMed).
Synonymes et noms alternatifs relatifs à MAX
CG9648 gene product from transcript CG9648-RD (Max), MYC associated factor X L homeolog (max.L), MYC associated factor X (MAX), MYC associated factor X (max), Max protein (Max), MYC associated factor X S homeolog (max.S), MYC associated factor X (Max), myc associated factor X (max), AA960152, AI875693, bhlhd4, bHLHd4, bhlhd5, bHLHd5, bhlhd6, bHLHd6, bhlhd7, bHLHd7, bhlhd8, bHLHd8, bHLHd9, CG9648, dMax, dmax, Dmel\\CG9648, fa92b04, fb52a04, fb95h11, MAX, max, wu:fa92b04, wu:fb52a04, wu:fb95h11, xmax, xmax2, xmax4, zmaxProtein level used designations for MAX
- CG9648-PA
- CG9648-PC
- Max-PA
- Max-PC
- Max homologue 2
- Myc binding protein Xmax4
- myc-associated factor X
- protein max
- xMAX
- MYC associated factor X
- myc-binding novel HLH/LZ protein
- protein myn
- class D basic helix-loop-helix protein 4
- Myc binding protein Xmax2
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