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MBNL1 Produits

(Muscleblind-like Protein 1 (MBNL1))
Involved in pre-mRNA alternative splicing regulation. Binds to CUG triplet repeat in RNA (By similarity).

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Catégories MBNL1 en vedette

MBNL1 Anticorps

High quality antibodies with extensive validation data.

MBNL1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MBNL1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MBNL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
N° du produit ABIN561753
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
N° du produit ABIN7264101
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF, IHC (p)
Validations
  • (3)
N° du produit ABIN574297
Quantité 50 μg
Fiche technique Fiche technique

MBNL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1143401
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1143402
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1143400
Quantité 96 tests
Fiche technique Fiche technique

MBNL1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
N° du produit ABIN2725584
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310480
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310482
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MBNL1

Coram, Stillwagon, Guggilam, Jenkins, Swanson, Ladd: "Muscleblind-like 1 is required for normal heart valve development in vivo." dans: BMC developmental biology, Vol. 15, pp. 36, (2015) (PubMed).

Rehman, Gladman, Periasamy, Sun, Mahadevan: "Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1)." dans: PLoS ONE, Vol. 9, Issue 4, pp. e95957, (2014) (PubMed).

Echeverria, Cooper: "Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron." dans: Nucleic acids research, Vol. 42, Issue 3, pp. 1893-903, (2014) (PubMed).

Sen, Talukdar, Liu, Tam, Reddy, Webster: "Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer." dans: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25426-37, (2010) (PubMed).

Arambula, Ramisetty, Baranger, Zimmerman: "A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16068-73, (2009) (PubMed).

Cardani, Baldassa, Botta, Rinaldi, Novelli, Mancinelli, Meola: "Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2." dans: Neuromuscular disorders : NMD, Vol. 19, Issue 5, pp. 335-43, (2009) (PubMed).

Holt, Jacquemin, Fardaei, Sewry, Butler-Browne, Furling, Brook, Morris: "Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle." dans: The American journal of pathology, Vol. 174, Issue 1, pp. 216-27, (2009) (PubMed).

Teplova, Patel: "Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1." dans: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1343-51, (2008) (PubMed).

Warf, Berglund: "MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T." dans: RNA (New York, N.Y.), Vol. 13, Issue 12, pp. 2238-51, (2007) (PubMed).

Adam-Vizi: "Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources." dans: Antioxidants & redox signaling, Vol. 7, Issue 9-10, pp. 1140-9, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à MBNL1

muscleblind like splicing regulator 1 (MBNL1), muscleblind like splicing regulator 1 (mbnl1), muscleblind-like splicing regulator 1 (mbnl1), muscleblind like splicing factor 1 (Mbnl1), muscleblind-like splicing regulator 1 (Mbnl1), EXP, EXP35, EXP40, EXP42, Mbnl, MBNL, MBNL1, mKIAA0428, zgc:153954

Protein level used designations for MBNL1

  • muscleblind-like
  • muscleblind-like (Drosophila)
  • muscleblind-like protein 1
  • muscleblind-like 1
  • triplet-expansion RNA-binding protein
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