MC1 Receptor Produits
(Melanocortin 1 Receptor (MC1R))
Catégories
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008].
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Catégories MC1 Receptor en vedette
MC1 Receptor Anticorps
High quality antibodies with extensive validation data.
MC1 Receptor Kits ELISA
Reliable ELISA kits for a wide range of species.
MC1 Receptor Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MC1 Receptor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7159233
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN686287
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC, IHC (fro)
Validations
- (3)
N° du produit
ABIN2856574
Quantité
100 μL
Fiche technique
Fiche technique
MC1 Receptor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6233295
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6233294
Quantité
96 tests
Fiche technique
Fiche technique
MC1 Receptor recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310505
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Mammalian Cells
Validations
N° du produit
ABIN7538382
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3099289
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits MC1 Receptor
: "Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants." dans: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4396467, (2018) (PubMed).: "Mechanistic Studies on the Use of Polygonum multiflorum for the Treatment of Hair Graying." dans: BioMed research international, Vol. 2015, pp. 651048, (2016) (PubMed).
: "Increased corticotropin-releasing hormone (CRH) expression in cutaneous lupus lesions." dans: Lupus, Vol. 24, Issue 8, pp. 854-61, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à MC1 Receptor
melanocortin 1 receptor (MC1R), melanocortin 1 receptor (Mc1r), melanocortin 1 receptor (mc1r), melanocortin 1 receptor (mc1r_par1), melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) (MC1R), CMM5, e, MC1-R, mc1r, MC1R, MSH-R, MSHR, Mshra, SHEP2, Tob, TUBB3Protein level used designations for MC1 Receptor
- MC1-R
- melanocyte-stimulating hormone receptor
- melanotropin receptor
- MSH-R
- extension recessive yellow
- melanocortin receptor 1
- melanocortin-1 receptor
- tobacco darkening
- BDF3
- alpha melanocyte stimulating hormone receptor
- melanocortin 1-receptor
- melanocyte stimulating hormone receptor
- melanocortin 1 receptor
- Melanotropin receptor
- Melanocortin receptor 1
- Melanocyte-stimulating hormone receptor
- tubulin, beta 3 class III
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