MCM8 Produits
(Minichromosome Maintenance Deficient 8 (MCM8))
Catégories
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Catégories MCM8 en vedette
MCM8 Anticorps
High quality antibodies with extensive validation data.
MCM8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MCM8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (3)
N° du produit
ABIN309831
Quantité
25 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN529702
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Bat, Cow, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
N° du produit
ABIN6737804
Quantité
100 μL
Fiche technique
Fiche technique
MCM8 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6211736
Quantité
96 tests
Fiche technique
Fiche technique
MCM8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1310565
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1990369
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505291
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MCM8
: "RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination." dans: Molecular cell, Vol. 66, Issue 5, pp. 622-634.e8, (2017) (PubMed).: "The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination." dans: Molecular and cellular biology, Vol. 33, Issue 8, pp. 1632-44, (2013) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." dans: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues." dans: Human pathology, Vol. 40, Issue 1, pp. 41-9, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à MCM8
minichromosome maintenance 8 homologous recombination repair factor (MCM8), minichromosome maintenance 8 homologous recombination repair factor (Mcm8), minichromosome maintenance 8 homologous recombination repair factor L homeolog (mcm8.L), 5730432L01Rik, C20orf154, dJ967N21.5Protein level used designations for MCM8
- DNA helicase MCM8
- DNA replication licensing factor MCM8
- MCM8 minichromosome maintenance deficient 8
- REC homolog
- minichromosome maintenance 8
- minichromosome maintenance deficient 8
- Minichromosome maintenance 8
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