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MCU Produits

(Mitochondrial Calcium Uniporter (MCU))
This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].

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Catégories MCU en vedette

MCU Anticorps

High quality antibodies with extensive validation data.

MCU Kits ELISA

Reliable ELISA kits for a wide range of species.

MCU Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MCU recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (4)
N° du produit ABIN7268549
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
N° du produit ABIN7146314
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (2)
N° du produit ABIN6260526
Quantité 100 μL
Fiche technique Fiche technique

MCU recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
N° du produit ABIN1744117
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1742896
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1773800
Quantité 96 tests
Fiche technique Fiche technique

MCU recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310583
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2713279
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MCU

Yan, Li, Yan, Zhao, Liu, Liu: "Effects of luteolin on regulatory proteins and enzymes for myocyte calcium circulation in hypothermic preserved rat heart." dans: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1433-1441, (2018) (PubMed).

Lee, Min, Kim, Song, Lim, Kim, Shin, Kang, Kang, Youn, Lee, An, Park, Lim, Kim, Kim, Park, Kim, Wang, Kim, Eom: "Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter." dans: EMBO reports, Vol. 16, Issue 10, pp. 1318-33, (2015) (PubMed).

Stauch, Purnell, Fox: "Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability." dans: Journal of proteome research, Vol. 13, Issue 5, pp. 2620-36, (2014) (PubMed).

Kovács-Bogdán, Sancak, Kamer, Plovanich, Jambhekar, Huber, Myre, Blower, Mootha: "Reconstitution of the mitochondrial calcium uniporter in yeast." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. 8985-90, (2014) (PubMed).

Arruda, Pers, Parlakgül, Güney, Inouye, Hotamisligil: "Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity." dans: Nature medicine, Vol. 20, Issue 12, pp. 1427-35, (2014) (PubMed).

Logan, Szabadkai, Sharpe, Parry, Torelli, Childs, Kriek, Phadke, Johnson, Roberts, Bonthron, Pysden, Whyte, Munteanu, Foley, Wheway, Szymanska, Natarajan, Abdelhamed, Morgan, Roper, Santen, Niks et al.: "Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. ..." dans: Nature genetics, Vol. 46, Issue 2, pp. 188-93, (2014) (PubMed).

Samanta, Douglas, Parekh: "Mitochondrial calcium uniporter MCU supports cytoplasmic Ca2+ oscillations, store-operated Ca2+ entry and Ca2+-dependent gene expression in response to receptor stimulation." dans: PLoS ONE, Vol. 9, Issue 7, pp. e101188, (2014) (PubMed).

Qiu, Tan, Hagenston, Martel, Kneisel, Skehel, Wyllie, Bading, Hardingham: "Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals." dans: Nature communications, Vol. 4, pp. 2034, (2013) (PubMed).

Pan, Liu, Nguyen, Liu, Sun, Teng, Fergusson, Rovira, Allen, Springer, Aponte, Gucek, Balaban, Murphy, Finkel: "The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter." dans: Nature cell biology, Vol. 15, Issue 12, pp. 1464-72, (2013) (PubMed).

Baughman, Perocchi, Girgis, Plovanich, Belcher-Timme, Sancak, Bao, Strittmatter, Goldberger, Bogorad, Koteliansky, Mootha: "Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter." dans: Nature, Vol. 476, Issue 7360, pp. 341-5, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à MCU

mitochondrial calcium uniporter (MCU), mitochondrial calcium uniporter (Mcu), 2010012O16Rik, AV064928, C10orf42, CCDC109A, Ccdc109a, D130073L02Rik, Gm64

Protein level used designations for MCU

  • calcium uniporter protein, mitochondrial
  • coiled-coil domain-containing protein 109A
  • coiled-coil domain containing 109A
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