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MDH1 Produits

(Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Catégories

This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009].

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Catégories MDH1 en vedette

MDH1 Anticorps

High quality antibodies with extensive validation data.

MDH1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MDH1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MDH1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (5)
N° du produit ABIN561768
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP, IHC
Validations
  • (3)
N° du produit ABIN7158940
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7158941
Quantité 100 μg
Fiche technique Fiche technique

MDH1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968431
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957626
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957627
Quantité 96 tests
Fiche technique Fiche technique

MDH1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123834
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310591
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310589
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MDH1

Paul, Gangwar, Bhargava, Ahmad: "STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient." dans: Redox biology, Vol. 14, pp. 423-438, (2018) (PubMed).

Schmitz, Llorens, Pracht, Thom, Correia, Zafar, Ferrer, Zerr: "Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients." dans: Aging, Vol. 8, Issue 11, pp. 2927-2935, (2017) (PubMed).

Burr, Costa, Grice, Timms, Lobb, Freisinger, Dodd, Dougan, Lehner, Frezza, Nathan: "Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions." dans: Cell metabolism, Vol. 24, Issue 5, pp. 740-752, (2016) (PubMed).

Nussbaumer, Asara, Teplytska, Murphy, Logan, Turck, Filiou: "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo." dans: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016) (PubMed).

Stiebler, Freitag, Schink, Stehlik, Tillmann, Ast, Bölker: "Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals." dans: PLoS genetics, Vol. 10, Issue 10, pp. e1004685, (2014) (PubMed).

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." dans: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Tanaka, Inazawa, Nakamura: "Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1)." dans: Genomics, Vol. 32, Issue 1, pp. 128-30, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à MDH1

malate dehydrogenase 1 (MDH1), malic enzyme 2 (ME2), malate dehydrogenase 1, NAD (soluble) (Mdh1), malate dehydrogenase 1 (Mdh1), malate dehydrogenase 1 S homeolog (mdh1.S), malate dehydrogenase, cytoplasmic (LOC100280767), Malate dehydrogenase 1 (Mdh1), B230377B03Rik, cMdh, D17921, MDH, Mdh, MDH-1, Mdh-1, MDH-s, mdh-s, Mdh2, MDHA, mdha, MdhD, Mdhl, MDL1, MGC:1375, Mor-2, MOR2, Mor2, mor2, ODS1, sMdh

Protein level used designations for MDH1

  • cytosolic malate dehydrogenase
  • diiodophenylpyruvate reductase
  • malate dehydrogenase, cytoplasmic
  • soluble malate dehydrogenase
  • NAD-ME
  • NAD-dependent malic enzyme, mitochondrial
  • malate dehydrogenase
  • pyruvic-malic carboxylase
  • malate dehydrogenase, soluble
  • Malate dehydrogenase-like enzyme
  • malate dehydrogenase 1, NAD (soluble)
  • malate dehydrogenase, peroxisomal
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