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MED1 Produits

(Mediator Complex Subunit 1 (MED1))
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008].

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Catégories MED1 en vedette

MED1 Anticorps

High quality antibodies with extensive validation data.

MED1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MED1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MED1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
N° du produit ABIN6256479
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6257759
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN562335
Quantité 100 μg
Fiche technique Fiche technique

MED1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648137
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1743266
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1774171
Quantité 96 tests
Fiche technique Fiche technique

MED1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310628
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418785
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Schizosaccharomyces pombe
Source Yeast
Validations
N° du produit ABIN1617063
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MED1

Brückmann, Bennedsen, Duijf, Terp, Thomassen, Larsen, Pedersen, Kruse, Alcaraz, Ditzel, Gjerstorff: "A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence." dans: Cell death & disease, Vol. 10, Issue 11, pp. 841, (2019) (PubMed).

Tabata, Rodgers, Hall, Lee, Jedrychowski, Gygi, Puigserver: "Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1? and MED1 complex." dans: Diabetes, Vol. 63, Issue 5, pp. 1519-32, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à MED1

mediator complex subunit 1 (MED1), calcitonin-related polypeptide beta (CALCB), mediator complex subunit 1 (med1), Mediator complex subunit 1 (MED1), mediator complex subunit 1 (Med1), mediator of RNA polymerase II transcription subunit 1 (med1), AI480703, CG7162, CRSP-1, CRSP1, crsp1, CRSP200, crsp200, CRSP210, Dmel\\CG7162, DRIP205, drip205, DRIP230, drip230, dTRAP220, l11Jus15, MED1, Med1, Med1/SOP3/TRAP220, nbr1, PBP, pbp, PPARBP, pparbp, Pparbp, PPARGBP, ppargbp, RB18A, rb18a, RGD1559552, TRAP220, trap220, Trap220, TRIP2, trip2

Protein level used designations for MED1

  • ARC205
  • PPAR binding protein
  • PPAR-binding protein
  • PPARG binding protein
  • TR-interacting protein 2
  • TRIP-2
  • activator-recruited cofactor 205 kDa component
  • mediator of RNA polymerase II transcription subunit 1
  • p53 regulatory protein RB18A
  • peroxisome proliferator-activated receptor-binding protein
  • thyroid hormone receptor-associated protein complex 220 kDa component
  • thyroid hormone receptor-associated protein complex component TRAP220
  • thyroid receptor interacting protein 2
  • thyroid receptor-interacting protein 2
  • vitamin D receptor-interacting protein 230 kD
  • vitamin D receptor-interacting protein complex component DRIP205
  • calcitonin receptor-stimulating peptide 1
  • calcitonin receptor-stimulating peptide-1
  • calcitonin-related polypeptide, beta
  • mediator complex subunit 1
  • peroxisome proliferator-activated receptor binding protein
  • membrane component, chromosome 17, surface marker 2
  • CG7162-PA
  • CG7162-PB
  • CG7162-PC
  • MED1-PA
  • MED1-PB
  • MED1-PC
  • mediator
  • Ppar binding protein
  • peroxisome proliferator activated receptor binding protein
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