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MED17 Produits

(Mediator Complex Subunit 17 (MED17))
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008].

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Catégories MED17 en vedette

MED17 Anticorps

High quality antibodies with extensive validation data.

MED17 Kits ELISA

Reliable ELISA kits for a wide range of species.

MED17 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MED17 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (5)
N° du produit ABIN564067
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7074579
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC, ChIP
Validations
  • (4)
N° du produit ABIN2778320
Quantité 100 μL
Fiche technique Fiche technique

MED17 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1743276
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1774181
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1744495
Quantité 96 tests
Fiche technique Fiche technique

MED17 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310642
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310641
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3093816
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MED17

Kikuchi, Umemura, Nishitani, Iida, Fukasawa, Hayashi, Hirose, Tanaka, Sugasawa, Ohkuma: "Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 3, pp. 191-202, (2015) (PubMed).

Tsutsui, Fukasawa, Shinmyouzu, Nakagawa, Tobe, Tanaka, Ohkuma: "Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes." dans: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 20955-65, (2013) (PubMed).

Tsutsui, Fukasawa, Tanaka, Hirose, Ohkuma: "Identification of target genes for the CDK subunits of the Mediator complex." dans: Genes to cells : devoted to molecular & cellular mechanisms, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à MED17

mediator of RNA polymerase II transcription subunit 17 (AOR_1_2446154), mediator of RNA polymerase II transcription subunit 17 (VDBG_01663), mediator complex subunit 17 (med17), mediator complex subunit 17 L homeolog (med17.L), mediator complex subunit 17 (MED17), mediator complex subunit 17 (Med17), 77kDa, C330002H14Rik, crsp6, CRSP6, Crsp6, CRSP77, DRIP80, TRAP80, Trap80

Protein level used designations for MED17

  • mediator of RNA polymerase II transcription subunit 17
  • Mediator of RNA polymerase II transcription subunit 17
  • CRSP complex subunit 6
  • cofactor required for Sp1 transcriptional activation subunit 6
  • cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa
  • ARC77
  • activator-recruited cofactor 77 kDa component
  • thyroid hormone receptor-associated protein complex 80 kDa component
  • transcriptional coactivator CRSP77
  • vitamin D3 receptor-interacting protein complex 80 kDa component
  • cofactor required for Sp1 transcriptional activation, subunit 6 (77kD)
  • cofactor required for Sp1 transcriptional activation, subunit 6
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