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MEF2C Produits

(Myocyte Enhancer Factor 2C (MEF2C))

Catégories

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010].

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Catégories MEF2C en vedette

MEF2C Anticorps

High quality antibodies with extensive validation data.

MEF2C Kits ELISA

Reliable ELISA kits for a wide range of species.

MEF2C Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MEF2C recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
N° du produit ABIN1098145
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IHC (p), ICC, IHC (fro), IP
Validations
  • (1)
  • (4)
N° du produit ABIN2856105
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (4)
N° du produit ABIN7260573
Quantité 200 μL
Fiche technique Fiche technique

MEF2C recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380846
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648633
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883753
Quantité 96 tests
Fiche technique Fiche technique

MEF2C recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124046
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310692
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505290
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MEF2C

Zhang, Zhang, Nam: "Stoichiometric optimization of Gata4, Hand2, Mef2c, and Tbx5 expression for contractile cardiomyocyte reprogramming." dans: Scientific reports, Vol. 9, Issue 1, pp. 14970, (2019) (PubMed).

Brown, Still, Koche, Yim, Takao, Cifani, Reed, Gunasekera, Ficarro, Romanienko, Mark, McCarthy, de Stanchina, Gonen, Seshan, Bhola, ODonnell, Spitzer, Stutzke, Lavallée, Hébert, Krivtsov, Melnick et al.: "MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia. ..." dans: Cancer discovery, Vol. 8, Issue 4, pp. 478-497, (2019) (PubMed).

Deczkowska, Matcovitch-Natan, Tsitsou-Kampeli, Ben-Hamo, Dvir-Szternfeld, Spinrad, Singer, David, Winter, Smith, Kertser, Baruch, Rosenzweig, Terem, Prinz, Villeda, Citri, Amit, Schwartz: "Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner." dans: Nature communications, Vol. 8, Issue 1, pp. 717, (2018) (PubMed).

Law, Leung, Yau, Tse, Wong, Leung, Mascheck, Huang, Sauer, Tsang et al.: "Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem ..." dans: International journal of cardiology, Vol. 168, Issue 4, pp. 3458-72, (2013) (PubMed).

Clark, Zhang, Lee, Evans, Lassar, Lee: "Evolutionary conservation of Nkx2.5 autoregulation in the second heart field." dans: Developmental biology, Vol. 374, Issue 1, pp. 198-209, (2013) (PubMed).

Lockhart, Wirrig, Phelps, Ghatnekar, Barth, Norris, Wessels: "Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart." dans: PLoS ONE, Vol. 8, Issue 2, pp. e57073, (2013) (PubMed).

Inagawa, Miyamoto, Yamakawa, Muraoka, Sadahiro, Umei, Wada, Katsumata, Kaneda, Nakade, Kurihara, Obata, Miyake, Fukuda, Ieda: "Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5." dans: Circulation research, Vol. 111, Issue 9, pp. 1147-56, (2012) (PubMed).

Xu, Cao, Wang, Xu, Chen, Xu: "VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27165, (2011) (PubMed).

Stephens, Stephens, Hobbs, Hutmacher, Bacic-Welsh, Woodruff, Morrison: "Myocyte enhancer factor 2c, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)-enhanced mineralization." dans: The Journal of biological chemistry, Vol. 286, Issue 34, pp. 30071-86, (2011) (PubMed).

Escher, Schorderet, Cottet: "Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice." dans: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5933-40, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à MEF2C

myocyte enhancer factor 2C (MEF2C), MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (mef2c), myocyte enhancer factor 2cb (mef2cb), MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) L homeolog (mef2c.L), myocyte enhancer factor 2C (Mef2c), myocyte enhancer factor 2ca (mef2ca), 5430401D19Rik, 9930028G15Rik, AV011172, C5DELq14.3, DEL5q14.3, id:ibd5026, Mef2, MEF2C, mef2c, RGD1563119, si:ch211-202e12.2, wu:fc05b06, XMEF2C, zgc:64184, zgc:85726

Protein level used designations for MEF2C

  • myocyte-specific enhancer factor 2C
  • myocyte enhancer factor 2C
  • myocyte-specific enhancer factor 2C-like
  • MADS box transcription enhancer factor 2, polypeptide C
  • MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)
  • Myocyte enhancer factor 2C protein
  • hoo
  • hoover
  • myocyte enhancer factor 2c
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