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Mesothelin Produits

(Mesothelin (MSLN))

Catégories

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].

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Catégories Mesothelin en vedette

Mesothelin Anticorps

High quality antibodies with extensive validation data.

Mesothelin Kits ELISA

Reliable ELISA kits for a wide range of species.

Mesothelin Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Mesothelin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC (f)
Validations
  • (7)
N° du produit ABIN6939032
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, FACS, IHC (p)
Validations
  • (5)
N° du produit ABIN727608
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, FACS
Validations
  • (5)
N° du produit ABIN7193453
Quantité 100 μL
Fiche technique Fiche technique

Mesothelin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957762
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957761
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6976025
Quantité 96 tests
Fiche technique Fiche technique

Mesothelin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275282
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275288
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275283
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Mesothelin

Li, Li, Xu, Xing, Ding, Jing, Wang, Hong: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." dans: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).

Duong, Wu, Green, Bavaghar-Zaeimi, Wang, Labib, Zhou, Cantu, Jeganathan, Popescu, Pantea, de Perrot, Kelley: "A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma." dans: EBioMedicine, Vol. 61, pp. 103031, (2021) (PubMed).

Makita, Kunii, Sakurai, Ihara, Motohashi, Suzuki, Nakayama, Okamoto: "Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer." dans: BMC cancer, Vol. 18, Issue 1, pp. 1254, (2019) (PubMed).

Hung, Xu, Li, Ma, Jin, Viley, Allen, Natarajan, Shivakumar, Peshwa, Emens: "Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy." dans: Human gene therapy, Vol. 29, Issue 5, pp. 614-625, (2019) (PubMed).

Sirois, Deny, Li, Fall, Moore: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." dans: Biotechnology and bioengineering, (2019) (PubMed).

Zhang, Yang, Gu, Wu, Chi, Liu, Wang, Xue, Qi, Sun, Zhang, Hu, Xu: "Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy." dans: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 102, (2018) (PubMed).

Zhang, Khanna, Jiang, Alewine, Miettinen, Pastan, Hassan: "Efficacy of Anti-mesothelin Immunotoxin RG7787 plus Nab-Paclitaxel against Mesothelioma Patient-Derived Xenografts and Mesothelin as a Biomarker of Tumor Response." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 6, pp. 1564-1574, (2018) (PubMed).

Oehl, Kresoja-Rakic, Opitz, Vrugt, Weder, Stahel, Wild, Felley-Bosco: "Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression." dans: Frontiers in oncology, Vol. 8, pp. 40, (2018) (PubMed).

Sirois, Deny, Baierl, George, Moore: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." dans: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).

Tang, Yang, Wang, Gu, Xia, Feng, Yang, Zhao, Su, Su, Wang: "Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy." dans: Oncotarget, Vol. 9, Issue 3, pp. 3895-3907, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à Mesothelin

mesothelin (MSLN), mesothelin (Msln), mesothelin (LOC611363), mesothelin (LOC100524016), MPF, MSLN, SMRP

Protein level used designations for Mesothelin

  • CAK1 antigen
  • megakaryocyte potentiating factor
  • pre-pro-megakaryocyte-potentiating factor
  • soluble MPF mesothelin related protein
  • ERC/mesothelin
  • protein expressed in renal carcinoma
  • mesothelin
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