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MGMT Produits

(O6-Methylguanine-DNA-Methyltransferase (MGMT))

Catégories

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a

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Catégories MGMT en vedette

MGMT Anticorps

High quality antibodies with extensive validation data.

MGMT Kits ELISA

Reliable ELISA kits for a wide range of species.

MGMT Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MGMT recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (7)
N° du produit ABIN5542437
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (4)
N° du produit ABIN730768
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7434551
Quantité 100 μL
Fiche technique Fiche technique

MGMT recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958286
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969037
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958287
Quantité 96 tests
Fiche technique Fiche technique

MGMT recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124248
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310882
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310884
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MGMT

Kotsarenko, Lylo, Ruban, Macewicz, Lukash: "Effects of Some Growth Factors and Cytokines on the Expression of the Repair Enzyme MGMT and Protein MARP in Human Cells In Vitro : Effect of Some Growth Factors and Cytokines." dans: Biochemical genetics, Vol. 56, Issue 5, pp. 459-477, (2018) (PubMed).

Koncar, Chu, Romick-Rosendale, Wells, Chan, Qi, Bahassi: "PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas." dans: Oncotarget, Vol. 8, Issue 9, pp. 15827-15837, (2017) (PubMed).

Altinoz, Elmaci, Bolukbasi, Ekmekci, Yenmis, Sari, Sav: "MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case." dans: Journal of chemotherapy (Florence, Italy), Vol. 29, Issue 4, pp. 238-244, (2017) (PubMed).

Yi, Liu, Xiang, Wang, Chen, Xie, Qi: "Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line." dans: Journal of the neurological sciences, Vol. 367, pp. 101-6, (2017) (PubMed).

Oktay, Ülgen, Can, Akyerli, Yüksel, Erdemgil, Durası, Henegariu, Nanni, Selevsek, Grossmann, Erson-Omay, Bai, Gupta, Lee, Turcan, Özpınar, Huse, Sav, Flanagan, Günel, Sezerman, Yakıcıer, Pamir et al.: "IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. ..." dans: Scientific reports, Vol. 6, pp. 27569, (2016) (PubMed).

Stepanenko, Andreieva, Korets, Mykytenko, Baklaushev, Huleyuk, Kovalova, Kotsarenko, Chekhonin, Vassetzky, Avdieiev, Dmitrenko: "Temozolomide promotes genomic and phenotypic changes in glioblastoma cells." dans: Cancer cell international, Vol. 16, pp. 36, (2016) (PubMed).

Ge, Guo, Zhang, Lin, Li, Liu, Kong, Fang, Zhao: "Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma." dans: Japanese journal of clinical oncology, (2015) (PubMed).

Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." dans: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." dans: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

Palmieri, Duchnowska, Woditschka, Hua, Qian, Biernat, Sosińska-Mielcarek, Gril, Stark, Hewitt, Liewehr, Steinberg, Jassem, Steeg: "Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 10, pp. 2727-39, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à MGMT

O-6-methylguanine-DNA methyltransferase (MGMT), O-6-methylguanine-DNA methyltransferase (Mgmt), Agat, AGT, AI267024

Protein level used designations for MGMT

  • 6-O-methylguanine-DNA methyltransferase
  • O-6-methylguanine-DNA-alkyltransferase
  • O6-methylguanine-DNA methyltransferase
  • methylated-DNA--protein-cysteine methyltransferase
  • methylguanine-DNA methyltransferase
  • O-6-alkylguanine-DNA alkyltransferase
  • 0-6-methylguanine-DNA methyltransferase
  • O(6)-alkylguanine-DNA alkyltransferase
  • O6-alkylguanine-DNA alkyltransferase
  • O6-methylguanine-DNA methyltranferase
  • O6-alkylguanine-DNA-alkyltransferase
  • O6-methylguanine-DNA-methyltransferase
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