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MICB Produits

(MHC Class I Polypeptide-Related Sequence B (MICB))

Catégories

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules\; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq, Jul 2008].

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Catégories MICB en vedette

MICB Anticorps

High quality antibodies with extensive validation data.

MICB Kits ELISA

Reliable ELISA kits for a wide range of species.

MICB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MICB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (1)
N° du produit ABIN1383988
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application IP
Validations
  • (1)
N° du produit ABIN517933
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN1327622
Quantité 50 μL
Fiche technique Fiche technique

MICB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975551
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1672867
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6719775
Quantité 1 kit
Fiche technique Fiche technique

MICB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN6964108
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275257
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275258
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MICB

Son, Lee, Koh, Shin, Bae, Yang, Park: "Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells." dans: Scientific reports, Vol. 6, pp. 32470, (2016) (PubMed).

Nielsen, Dyring-Andersen, Schmidt, Witherden, Lovato, Woetmann, Ødum, Poulsen, Havran, Geisler, Bonefeld: "NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity." dans: The Journal of investigative dermatology, Vol. 135, Issue 5, pp. 1311-9, (2015) (PubMed).

Giannattasio, Weil, Kloess, Ansari, Stelzer, Cerwenka, Steinle, Koehl, Koch: "Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids." dans: BMC cancer, Vol. 15, pp. 351, (2015) (PubMed).

Zingoni, Cecere, Vulpis, Fionda, Molfetta, Soriani, Petrucci, Ricciardi, Fuerst, Amendola, Mytilineos, Cerboni, Paolini, Cippitelli, Santoni: "Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 2, pp. 736-48, (2015) (PubMed).

Esteso, Luzón, Sarmiento, Gómez-Caro, Steinle, Murphy, Carbone, Valés-Gómez, Reyburn: "Altered microRNA expression after infection with human cytomegalovirus leads to TIMP3 downregulation and increased shedding of metalloprotease substrates, including MICA." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 3, pp. 1344-52, (2014) (PubMed).

Gómez-Lomelí, Bravo-Cuellar, Hernández-Flores, Jave-Suárez, Aguilar-Lemarroy, Lerma-Díaz, Domínguez-Rodríguez, Sánchez-Reyes, Ortiz-Lazareno: "Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor." dans: Cancer cell international, Vol. 14, Issue 1, pp. 100, (2014) (PubMed).

Nachmani, Zimmermann, Oiknine Djian, Weisblum, Livneh, Khanh Le, Galun, Horejsi, Isakov, Shomron, Wolf, Hengel, Mandelboim: "MicroRNA editing facilitates immune elimination of HCMV infected cells." dans: PLoS pathogens, Vol. 10, Issue 2, pp. e1003963, (2014) (PubMed).

Fielding, Aicheler, Stanton, Wang, Han, Seirafian, Davies, McSharry, Weekes, Antrobus, Prodhomme, Blanchet, Sugrue, Cuff, Roberts, Davison, Lehner, Wilkinson, Tomasec: "Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation." dans: PLoS pathogens, Vol. 10, Issue 5, pp. e1004058, (2014) (PubMed).

Leung, Vong, Lin, Janke, Chen, Leung: "Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXR? activation." dans: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2675-92, (2013) (PubMed).

Madrid, Ganem: "Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44." dans: Journal of virology, Vol. 86, Issue 16, pp. 8693-704, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à MICB

MHC class I polypeptide-related sequence B (MICB), MHC class I-related protein-like (LOC512825), PERB11.2

Protein level used designations for MICB

  • MHC class I chain-related protein B
  • MHC class I mic-B antigen
  • MHC class I-like molecule PERB11.2-IMX
  • MIC-B
  • stress inducible class I homolog
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