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MID1 Produits

(Midline 1 (MID1))
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing\; however, the full-length nature of some of the variants has not been determined. [provided by RefSeq, Jul 2010].

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Catégories MID1 en vedette

MID1 Anticorps

High quality antibodies with extensive validation data.

MID1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MID1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MID1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6265724
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7188874
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7151071
Quantité 100 μL
Fiche technique Fiche technique

MID1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957836
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648016
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5656907
Quantité 96 tests
Fiche technique Fiche technique

MID1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310921
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7413310
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3074726
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MID1

Bell, Malyukova, Holien, Koach, Parker, Kavallaris, Marshall, Cheung: "TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members." dans: PLoS ONE, Vol. 7, Issue 5, pp. e37470, (2012) (PubMed).

Liu, Knutzen, Krauss, Schweiger, Chiang: "Control of mTORC1 signaling by the Opitz syndrome protein MID1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 21, pp. 8680-5, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à MID1

midline 1 (MID1), midline 1 (Mid1), midline 1 (mid1), midline 1 L homeolog (mid1.L), 61B3-R, BBBG1, bbbg1, DXHXS1141, FXY, Fxy, fxy, GBBB1, gbbb1, MIDIN, midin, Midline1, OGS1, ogs1, OS, OSX, osx, RNF59, rnf59, TRIM18, Trim18, trim18, XPRF, xprf, ZNFXY, znfxy

Protein level used designations for MID1

  • RING finger protein 59
  • midline 1 RING finger protein
  • midline-1
  • putative transcription factor XPRF
  • tripartite motif protein TRIM18
  • tripartite motif-containing protein 18
  • zinc finger on X and Y, mouse, homolog of
  • midin
  • Finger on X and Y (in rat only on X)
  • E3 ubiquitin-protein ligase Midline-1
  • midline 1 (Opitz/BBB syndrome)
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