Minichromosome Maintenance Complex Component 3 Produits
(Minichromosome Maintenance Complex Component 3 (MCM3))
Catégories
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
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Catégories Minichromosome Maintenance Complex Component 3 en vedette
Minichromosome Maintenance Complex Component 3 Anticorps
High quality antibodies with extensive validation data.
Minichromosome Maintenance Complex Component 3 Kits ELISA
Reliable ELISA kits for a wide range of species.
Minichromosome Maintenance Complex Component 3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Minichromosome Maintenance Complex Component 3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (11)
N° du produit
ABIN561761
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (7)
N° du produit
ABIN3021327
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
N° du produit
ABIN7268540
Quantité
100 μL
Fiche technique
Fiche technique
Minichromosome Maintenance Complex Component 3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957841
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5656914
Quantité
96 tests
Fiche technique
Fiche technique
Minichromosome Maintenance Complex Component 3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1310549
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505054
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7420189
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Minichromosome Maintenance Complex Component 3
: "Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells." dans: Toxicology letters, Vol. 209, Issue 1, pp. 58-66, (2012) (PubMed).: "High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma." dans: Diagnostic pathology, Vol. 7, pp. 82, (2012) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." dans: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "MCM proteins are negative regulators of hypoxia-inducible factor 1." dans: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." dans: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).
: "BID binds to replication protein A and stimulates ATR function following replicative stress." dans: Molecular and cellular biology, Vol. 31, Issue 21, pp. 4298-309, (2011) (PubMed).
: "Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24." dans: Blood, Vol. 111, Issue 10, pp. 5215-22, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à Minichromosome Maintenance Complex Component 3
minichromosome maintenance complex component 3 (MCM3), MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) (mcm3), minichromosome maintenance complex component 3 (mcm3), minichromosome maintenance complex component 3 (Mcm3), Minichromosome maintenance 3 (Mcm3), minichromosome maintenance complex component 3 L homeolog (mcm3.L), MCM complex subunit Mcm3 (mcm3), AL033361, C80350, cb32, CG4206, chunp6867, dMCM3, Dmel\\CG4206, DmeMCM3, DmMCM3, DmMcm3, HCC5, MCM3, McM3, Mcmd, Mcp-PCR2, P1, P1-MCM3, P1.h, p1.m, PCR2, RLFB, wu:fa26g03, xmcm3Protein level used designations for Minichromosome Maintenance Complex Component 3
- DNA polymerase alpha holoenzyme-associated protein P1
- DNA replication factor MCM3
- DNA replication licensing factor MCM3
- MCM3 minichromosome maintenance deficient 3
- RLF subunit beta
- cervical cancer proto-oncogene 5
- hRlf beta subunit
- minichromosome maintenance deficient 3
- p102
- replication licensing factor, beta subunit
- zMCM3
- zygotic DNA replication licensing factor mcm3
- zygotic minichromosome maintenance protein 3
- P1-MCM3
- mini chromosome maintenance deficient
- CG4206-PA
- Mcm3-PA
- minichromosome maintenance 3
- minichromosome maintenance-PCR2
- P1 homolog
- XRLF subunit beta
- mMCM3
- maternal DNA replication licensing factor mcm3
- maternal minichromosome maintenance protein 3
- p100
- Minichromosome maintenance protein 3
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