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Mitogen-Activated Protein Kinase Produits

(Mitogen-Activated Protein Kinase (MAPK))
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the MAPK/ERK cascade. Depending on the cellular context, this cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The the MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. Many of the substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC)\; as well as in the fragmentation of the Golgi apparatus during mitosis. Phosphorylates microtubule-associated protein 2 (MAP2), myelin basic protein (MBP), and Elk-1. Activated by M phase promoting factor (MPF).

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Catégories Mitogen-Activated Protein Kinase en vedette

Mitogen-Activated Protein Kinase Anticorps

High quality antibodies with extensive validation data.

Mitogen-Activated Protein Kinase Kits ELISA

Reliable ELISA kits for a wide range of species.

Mitogen-Activated Protein Kinase recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique

Application WB
Validations
N° du produit ABIN2473488
Quantité 0.1 mL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
N° du produit ABIN347177
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB
Validations
N° du produit ABIN5688866
Quantité 0.1 mL
Fiche technique Fiche technique

Mitogen-Activated Protein Kinase recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968637
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN775555
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN777520
Quantité 96 tests
Fiche technique Fiche technique

Dernières publications sur nos produits Mitogen-Activated Protein Kinase

Cseh, Doma, Baccarini: ""RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway." dans: FEBS letters, Vol. 588, Issue 15, pp. 2398-406, (2014) (PubMed).

Tanoue, Nishida: "Molecular recognitions in the MAP kinase cascades." dans: Cellular signalling, Vol. 15, Issue 5, pp. 455-62, (2003) (PubMed).

Johnson, Lapadat: "Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases." dans: Science (New York, N.Y.), Vol. 298, Issue 5600, pp. 1911-2, (2002) (PubMed).

Adams, Sweatt: "Molecular psychology: roles for the ERK MAP kinase cascade in memory." dans: Annual review of pharmacology and toxicology, Vol. 42, pp. 135-63, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à Mitogen-Activated Protein Kinase

mitogen-activated protein kinase (Tc00.1047053506229.10), mitogen-activated protein kinase (Tb927.6.1780), mitogen-activated protein kinase (Tb927.8.3770), mitogen-activated protein kinase 1 S homeolog (mapk1.S), erk, erk2, ert1, mapk, mapk1, mapk1a, mapk2, mpk1, p42mapk, prkm1, prkm2, Tb06.28P18.710, Tb08.10J17.560, xp42

Protein level used designations for Mitogen-Activated Protein Kinase

  • mitogen-activated protein kinase
  • MAP kinase
  • mitogen-activated protein kinase 1a
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