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MKL1 Produits

(Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Catégories

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq, Jul 2008].

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Catégories MKL1 en vedette

MKL1 Anticorps

High quality antibodies with extensive validation data.

MKL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (3)
N° du produit ABIN6143855
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (2)
N° du produit ABIN1387286
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
N° du produit ABIN6259116
Quantité 100 μL
Fiche technique Fiche technique

MKL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968520
Quantité 96 tests
Fiche technique Fiche technique

Dernières publications sur nos produits MKL1

Whitson, Lee, Urman, Mirza, Yao, Brown, Li, Shankar, Fry, Atwood, Lee, Hollmig, Aasi, Sarin, Scott, Epstein, Tang, Oro: "Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas." dans: Nature medicine, Vol. 24, Issue 3, pp. 271-281, (2018) (PubMed).

Gjorevski, Piotrowski, Varner, Nelson: "Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices." dans: Scientific reports, Vol. 5, pp. 11458, (2015) (PubMed).

Record, Malinova, Zenner, Plagnol, Nowak, Syed, Bouma, Curtis, Gilmour, Cale, Hackett, Charras, Moulding, Nejentsev, Thrasher, Burns: "Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1." dans: Blood, Vol. 126, Issue 13, pp. 1527-35, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Schmidt, Duncan, Yadav, Regan, Verone, Lohse, Pop, Attwood, Wilding, Mohler, Sebo, Tindall, Heemers: "RhoA as a mediator of clinically relevant androgen action in prostate cancer cells." dans: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 5, pp. 716-35, (2012) (PubMed).

Muehlich, Hampl, Khalid, Singer, Frank, Breuhahn, Gudermann, Prywes: "The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1." dans: Oncogene, Vol. 31, Issue 35, pp. 3913-23, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à MKL1

megakaryoblastic leukemia (translocation) 1 (MKL1), megakaryoblastic leukemia 1 protein (mkl1), megakaryoblastic leukemia (translocation) 1 (Mkl1), megakaryoblastic leukemia (translocation) 1 S homeolog (mkl1.S), MKL (megakaryoblastic leukemia)/myocardin-like 1 (Mkl1), AI852829, AMKL, AW743281, AW821984, BSAC, Bsac, MAL, Mal, MKL1, MRTF-A, Mrtf-a, mrtf-a, Mrtf-A, mrtfa

Protein level used designations for MKL1

  • megakaryoblastic leukemia 1 protein
  • MKL/myocardin-like protein 1
  • RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein
  • basic, SAP and coiled-coil domain
  • megakaryocytic acute leukemia protein
  • myocardin-related transcription factor A
  • xMRTF-A
  • basic SAP and coiled-coil domains
  • basic SAP coiled-coil transcription activator
  • megakaryoblastic leukemia (translocation) 1 homolog
  • megakaryoblastic leukemia 1 protein homolog
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