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MLL2 Produits

(Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Catégories

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008].

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Catégories MLL2 en vedette

MLL2 Anticorps

High quality antibodies with extensive validation data.

MLL2 Kits ELISA

Reliable ELISA kits for a wide range of species.

MLL2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC (p), WB
Validations
  • (3)
  • (3)
N° du produit ABIN6243263
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (1)
N° du produit ABIN948660
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC (p), IHC
Validations
  • (2)
N° du produit ABIN1494780
Quantité 50 μg
Fiche technique Fiche technique

MLL2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503544
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503545
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503546
Quantité 96 tests
Fiche technique Fiche technique

MLL2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311012
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MLL2

Micale, Augello, Maffeo, Selicorni, Zucchetti, Fusco, De Nittis, Pellico, Mandriani, Fischetto, Boccone, Silengo, Biamino, Perria, Sotgiu, Serra, Lapi, Neri, Ferlini, Cavaliere, Chiurazzi, Monica et al.: "Molecular analysis, pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients. ..." dans: Human mutation, Vol. 35, Issue 7, pp. 841-50, (2014) (PubMed).

Kim, Sharma, Dhar, Lee, Gu, Chan, Lin, Lee: "UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells." dans: Cancer research, Vol. 74, Issue 6, pp. 1705-17, (2014) (PubMed).

Bhan, Hussain, Ansari, Bobzean, Perrotti, Mandal: "Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo." dans: The Journal of steroid biochemistry and molecular biology, Vol. 141, pp. 160-70, (2014) (PubMed).

Dhar, Lee, Kan, Voigt, Ma, Shi, Reinberg, Lee: "Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4." dans: Genes & development, Vol. 26, Issue 24, pp. 2749-62, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à MLL2

lysine methyltransferase 2D (KMT2D), lysine methyltransferase 2B (KMT2B), lysine (K)-specific methyltransferase 2D (Kmt2d), myeloid/lymphoid or mixed-lineage leukemia 2 (MLL2), lysine methyltransferase 2D (Kmt2d), AAD10, ALR, BC032281, BC058659, C430014K11Rik, CAGL114, HRX2, KABUK1, KMS, KMT2B, MLL1B, MLL2, Mll2, MLL4, Mll4, TNRC21, TRX2, WBP7

Protein level used designations for MLL2

  • ALL1-related protein
  • Kabuki make-up syndrome
  • Kabuki mental retardation syndrome
  • histone-lysine N-methyltransferase 2D
  • histone-lysine N-methyltransferase MLL2
  • lysine N-methyltransferase 2D
  • myeloid/lymphoid or mixed-lineage leukemia 2
  • trinucleotide repeat containing 21
  • KMT2D
  • WBP-7
  • WW domain binding protein 7
  • WW domain-binding protein 7
  • histone-lysine N-methyltransferase 2B
  • histone-lysine N-methyltransferase MLL4
  • lysine N-methyltransferase 2B
  • mixed lineage leukemia gene homolog 2
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4
  • myeloid/lymphoid or mixed-lineage leukemia 4
  • myeloid/lymphoid or mixed-lineage leukemia protein 4
  • trithorax homolog 2
  • trithorax homologue 2
  • myeloid/lymphoid or mixed-lineage leukemia protein 2
  • LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D
  • lysine (K)-specific methyltransferase 2D
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