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MLL4 Produits

(Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Catégories

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008].

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Catégories MLL4 en vedette

MLL4 Anticorps

High quality antibodies with extensive validation data.

MLL4 Kits ELISA

Reliable ELISA kits for a wide range of species.

MLL4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN564215
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application IHC (p)
Validations
N° du produit ABIN6388423
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
N° du produit ABIN5620182
Quantité 100 μL
Fiche technique Fiche technique

MLL4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503557
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503558
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503559
Quantité 96 tests
Fiche technique Fiche technique

MLL4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
N° du produit ABIN7509078
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MLL4

Malik, Khan, Asangani, Cieślik, Prensner, Wang, Iyer, Jiang, Borkin, Escara-Wilke, Stender, Wu, Niknafs, Jing, Qiao, Palanisamy, Kunju, Krishnamurthy, Yocum, Mellacheruvu, Nesvizhskii, Cao et al.: "Targeting the MLL complex in castration-resistant prostate cancer. ..." dans: Nature medicine, Vol. 21, Issue 4, pp. 344-52, (2015) (PubMed).

Huntsman, Chin, Muleris, Batley, Collins, Wiedemann, Aparicio, Caldas: "MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines." dans: Oncogene, Vol. 18, Issue 56, pp. 7975-84, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à MLL4

lysine methyltransferase 2B (KMT2B), lysine (K)-specific methyltransferase 2B (Kmt2b), lysine (K)-specific methyltransferase 2D (Kmt2d), lysine methyltransferase 2B (Kmt2b), 2610014H22Rik, ALR, BC032281, BC058659, C430014K11Rik, HRX2, KMT2B, mKIAA0304, MLL1B, MLL2, Mll2, MLL4, Mll4, RGD1308331, TRX2, WBP7, Wbp7

Protein level used designations for MLL4

  • KMT2D
  • WBP-7
  • WW domain binding protein 7
  • WW domain-binding protein 7
  • histone-lysine N-methyltransferase 2B
  • histone-lysine N-methyltransferase MLL4
  • lysine N-methyltransferase 2B
  • lysine N-methyltransferase 2D
  • mixed lineage leukemia gene homolog 2
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4
  • myeloid/lymphoid or mixed-lineage leukemia 4
  • myeloid/lymphoid or mixed-lineage leukemia protein 4
  • trithorax homolog 2
  • trithorax homologue 2
  • mixed lineage leukemia 2
  • myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog
  • ALL1-related protein
  • histone-lysine N-methyltransferase 2D
  • histone-lysine N-methyltransferase MLL2
  • myeloid/lymphoid or mixed-lineage leukemia 2
  • myeloid/lymphoid or mixed-lineage leukemia protein 2
  • LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
  • histone-lysine N-methyltransferase 2B-like
  • lysine (K)-specific methyltransferase 2B
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