MLLT11 Produits
(Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
Catégories
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1\;11)(q21\;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008].
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Catégories MLLT11 en vedette
MLLT11 Anticorps
High quality antibodies with extensive validation data.
MLLT11 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MLLT11 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, WB
Validations
- (5)
- (2)
N° du produit
ABIN564754
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (2)
N° du produit
ABIN1387553
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (2)
N° du produit
ABIN7074715
Quantité
100 μL
Fiche technique
Fiche technique
MLLT11 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124041
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311017
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN5853757
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MLLT11
: "MLLT11/AF1q is differentially expressed in maturing neurons during development." dans: Gene expression patterns : GEP, Vol. 15, Issue 2, pp. 80-7, (2014) (PubMed).: "AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39968, (2012) (PubMed).
: "AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway." dans: Blood, Vol. 118, Issue 7, pp. 1784-96, (2011) (PubMed).
: "Identification of the functional role of AF1Q in the progression of breast cancer." dans: Breast cancer research and treatment, Vol. 111, Issue 1, pp. 65-78, (2008) (PubMed).
: "Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway." dans: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3160-8, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à MLLT11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11), MLLT11, transcription factor 7 cofactor (MLLT11), myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (Mllt11), MLLT11, transcription factor 7 cofactor (Mllt11), MLLT11, transcription factor 7 cofactor (mllt11), AF1Q, Af1q, AI839562, fc23g02, RGD1305525, RP11-316M1.10, si:ch211-210h11.4, wu:fc23g02, Zfp692Protein level used designations for MLLT11
- protein AF1q
- ALL1 fused gene from chromosome 1q
- ALL1-fused gene from chromosome 1q
- zinc finger protein 692
- AF1Q protein
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