MME Produits
(Membrane Metallo-Endopeptidase (MME))
Catégories
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008].
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Catégories MME en vedette
MME Anticorps
High quality antibodies with extensive validation data.
MME Kits ELISA
Reliable ELISA kits for a wide range of species.
MME Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MME recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (1)
- (6)
N° du produit
ABIN1724914
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (6)
N° du produit
ABIN6143900
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7434053
Quantité
100 μL
Fiche technique
Fiche technique
MME recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (4)
N° du produit
ABIN6730947
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957745
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957744
Quantité
96 tests
Fiche technique
Fiche technique
MME recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275263
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275264
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275262
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MME
: "Increased granulocyte membrane neprilysin (CD10) expression is associated with better prognosis in heart failure." dans: European journal of heart failure, Vol. 21, Issue 4, pp. 537-539, (2020) (PubMed).: "Soluble neprilysin, NT-proBNP, and growth differentiation factor-15 as biomarkers for heart failure in dialysis patients (SONGBIRD)." dans: Clinical research in cardiology : official journal of the German Cardiac Society, Vol. 109, Issue 8, pp. 1035-1047, (2020) (PubMed).
: "Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression." dans: Phytotherapy research : PTR, Vol. 33, Issue 4, pp. 1114-1121, (2019) (PubMed).
: "Cinacalcet attenuated bone loss via inhibiting parathyroid hormone-induced endothelial-to-adipocyte transition in chronic kidney disease rats." dans: Annals of translational medicine, Vol. 7, Issue 14, pp. 312, (2019) (PubMed).
: "Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation." dans: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).
: "Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report." dans: Experimental and therapeutic medicine, Vol. 16, Issue 3, pp. 2060-2065, (2018) (PubMed).
: "Improved glycaemia in high-fat-fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels." dans: Diabetologia, Vol. 60, Issue 4, pp. 701-708, (2017) (PubMed).
: "Soluble neprilysin does not correlate with outcome in heart failure with preserved ejection fraction." dans: European journal of heart failure, Vol. 18, Issue 1, pp. 89-93, (2016) (PubMed).
: "A Test in Context: Neprilysin: Function, Inhibition, and Biomarker." dans: Journal of the American College of Cardiology, Vol. 68, Issue 6, pp. 639-53, (2016) (PubMed).
: "A metanephric adenoma of the kidney associated with polycythemia: A case report." dans: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à MME
membrane metalloendopeptidase (MME), membrane metallo endopeptidase (Mme), membrane metallo-endopeptidase (Mme), membrane metalloendopeptidase (Mme), 6030454K05Rik, C85356, CALLA, CD10, NEP, Nep, neprilysin, SFEProtein level used designations for MME
- atriopeptidase
- common acute lymphocytic leukemia antigen
- enkephalinase
- membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
- membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
- membrane metallo-endopeptidase variant 1
- membrane metallo-endopeptidase variant 2
- neprilysin
- neutral endopeptidase 24.11
- skin fibroblast elastase
- common acute lymphoblastic leukemia antigen
- neutral endopeptidase
- neprilysin-410 short isoform
- membrane metallo endopeptidase
- NEP
- membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase)
- LOW QUALITY PROTEIN: neprilysin
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