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MPRIP Produits

(Myosin Phosphatase rho Interacting Protein (MPRIP))

Catégories

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells.

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Catégories MPRIP en vedette

MPRIP Anticorps

High quality antibodies with extensive validation data.

MPRIP recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN5066423
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN5066422
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (1)
N° du produit ABIN2476368
Quantité 0.1 mg
Fiche technique Fiche technique

MPRIP recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6210136
Quantité 96 tests
Fiche technique Fiche technique

MPRIP recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3134700
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MPRIP

Wu, Chung, Cao, Jin, Edmiston, Hickman, Levy, Whalen, Abrams, Degterev, Lo, Tozzi, Kaplan, El Khoury, Whalen: "Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis." dans: Cell death & disease, Vol. 12, Issue 11, pp. 1064, (2021) (PubMed).

Komatsu, Wang, Seow, Ikebe: "p116Rip promotes myosin phosphatase activity in airway smooth muscle cells." dans: Journal of cellular physiology, (2019) (PubMed).

Nakamuta, Yang, Wang, Gallo, Yu, Tai, Van Aelst: "Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain." dans: The Journal of cell biology, Vol. 216, Issue 12, pp. 4313-4330, (2017) (PubMed).

Seifert, Werba, Tiwari, Giao Ly, Alothman, Alqunaibit, Avanzi, Barilla, Daley, Greco, Torres-Hernandez, Pergamo, Ochi, Zambirinis, Pansari, Rendon, Tippens, Hundeyin, Mani, Hajdu, Engle, Miller: "The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression." dans: Nature, Vol. 532, Issue 7598, pp. 245-9, (2016) (PubMed).

Saligrama, Fortner, Secinaro, Collins, Russell, Budd: "IL-15 maintains T-cell survival via S-nitrosylation-mediated inhibition of caspase-3." dans: Cell death and differentiation, Vol. 21, Issue 6, pp. 904-14, (2014) (PubMed).

Vitner, Salomon, Farfel-Becker, Meshcheriakova, Ali, Klein, Platt, Cox, Futerman: "RIPK3 as a potential therapeutic target for Gaucher's disease." dans: Nature medicine, Vol. 20, Issue 2, pp. 204-8, (2014) (PubMed).

Kung, Dai, Deng, Kitsis: "A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis." dans: Cell death and differentiation, Vol. 21, Issue 4, pp. 634-44, (2014) (PubMed).

Bracken, Li, Wright, Lawrence, Pillman, Salmanidis, Anderson, Dredge, Gregory, Tsykin, Neilsen, Thomson, Bert, Leerberg, Yap, Jensen, Khew-Goodall, Goodall: "Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion." dans: The EMBO journal, Vol. 33, Issue 18, pp. 2040-56, (2014) (PubMed).

McQuade, Cho, Chan: "Positive and Negative Phosphorylation Regulates RIP1 and RIP3-Induced Programmed Necrosis." dans: The Biochemical journal, (2013) (PubMed).

Moquin, McQuade, Chan: "CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis." dans: PLoS ONE, Vol. 8, Issue 10, pp. e76841, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à MPRIP

myosin phosphatase Rho interacting protein (MPRIP), myosin phosphatase Rho interacting protein (Mprip), 9530046C02, AA536749, AI647711, C76423, M-RIP, M-rip, mKIAA0864, MRIP, Mrip, p116Rip, RHOIP3, Rhoip3, RIP3

Protein level used designations for MPRIP

  • Rho interacting protein 3
  • myosin phosphatase Rho-interacting protein
  • Rho-interacting protein 3 (p116RIP) (RIP3)
  • p116 Rho interacting protein
  • RIP3
  • myosin phosphatase-Rho interacting protein
  • rho-interacting protein 3
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