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MUC5B Produits

(Mucin 5 Subtype B (MUC5B))
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010].

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Catégories MUC5B en vedette

MUC5B Anticorps

High quality antibodies with extensive validation data.

MUC5B Kits ELISA

Reliable ELISA kits for a wide range of species.

MUC5B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MUC5B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7429016
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, FACS
Validations
  • (5)
N° du produit ABIN7193318
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
N° du produit ABIN7193568
Quantité 100 μL
Fiche technique Fiche technique

MUC5B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957907
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
N° du produit ABIN6957906
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957908
Quantité 96 tests
Fiche technique Fiche technique

MUC5B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311644
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7505621
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7411138
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MUC5B

Bianchi, Sivarajan, Walles, Hackenberg, Steinke: "Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions." dans: Innate immunity, Vol. 27, Issue 1, pp. 89-98, (2022) (PubMed).

Fang, Uchiyama, Sakai, Hara, Tsutsui, Suda, Mitsuyama, Kawamura, Tsuchiya: "ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism." dans: Mucosal immunology, Vol. 12, Issue 5, pp. 1092-1103, (2020) (PubMed).

Pushpass, Pellicciotta, Kelly, Proctor, Carpenter: "Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model." dans: Nutrients, Vol. 11, Issue 10, (2019) (PubMed).

Zhang, Derycke, Holtappels, Wang, Zhang, Bachert, Zhang: "Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps." dans: Allergy, Vol. 74, Issue 1, pp. 131-140, (2019) (PubMed).

Chaker, Zissler, Poulos, Wagenmann, Bas, Gürth, Xanthou, Schmidt-Weber: "Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease." dans: International archives of allergy and immunology, Vol. 176, Issue 1, pp. 15-25, (2018) (PubMed).

Guan, Zhu, Shen, Jia, Jin, Dong, Xie: "Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling." dans: European journal of pharmacology, Vol. 824, pp. 30-39, (2018) (PubMed).

Navarrete, Palacios, Aguilar-Salvatierra, Guardia, Gómez-Moreno: "Effect of Inhaled Corticosteroids on Salival Composition: A Cross-Sectional Study in Patients with Bronchial Asthma." dans: Clinical drug investigation, Vol. 35, Issue 9, pp. 569-74, (2015) (PubMed).

Du, Richmond, Blackwell, Cates, Massion, Ware, Lee, Kononov, Lawson, Blackwell, Polosukhin: "Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease." dans: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 6, pp. 657-665, (2015) (PubMed).

Sibila, Suarez-Cuartin, Rodrigo-Troyano, Fardon, Finch, Mateus, Garcia-Bellmunt, Castillo, Vidal, Sanchez-Reus, Restrepo, Chalmers: "Secreted mucins and airway bacterial colonization in non-CF bronchiectasis." dans: Respirology (Carlton, Vic.), Vol. 20, Issue 7, pp. 1082-8, (2015) (PubMed).

Fields, Song, Rasoul, Fong, Works, Shew, Yiu, Mirsalis, DAndrea: "New candidate biomarkers in the female genital tract to evaluate microbicide toxicity." dans: PLoS ONE, Vol. 9, Issue 10, pp. e110980, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à MUC5B

mucin 5B, oligomeric mucus/gel-forming (MUC5B), mucin 5B, oligomeric mucus/gel-forming (Muc5b), ovomucin, alpha subunit (LOC395381), mucin 5AC, oligomeric mucus/gel-forming (MUC5AC), mucin 5B, oligomeric mucus/gel-forming (muc5b), mucin-5B (LOC100498539), mucin 5, subtype B, tracheobronchial (Muc5b), 2300002I04Rik, A130042M24, AV085033, MG1, MUC-5B, MUC5, MUC5B, MUC9, mucin 5b, RGD1561983

Protein level used designations for MUC5B

  • cervical mucin MUC5B
  • high molecular weight salivary mucin MG1
  • mucin 5, subtype B, tracheobronchial
  • mucin-5B
  • sublingual gland mucin
  • ovomucin
  • ovomucin, alpha-subunit
  • mucin 5B, oligomeric mucus/gel-forming
  • mucin protein
  • mucin 5, subtype B, tracheobronchial-like
  • mucin-5B-like
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