Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008].
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Dernières publications sur nos produits Multimerin 1
Mizrachi Nebenzahl, Blau, Kushnir, Shagan, Portnoi, Cohen, Azriel, Malka, Adawi, Kafka, Dotan, Guterman, Troib, Fishilevich, Gershoni, Braiman, Mitchell, Mitchell, Porat, Goliand, Chalifa Caspi et al.: "Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as ..." dans: PLoS ONE, Vol. 11, Issue 3, pp. e0150320, (2016) (PubMed).
Al-Daghri, Alokail, Manousopoulou, Heinson, Al-Attas, Al-Saleh, Sabico, Yakout, Woelk, Chrousos, Garbis: "Sex-specific vitamin D effects on blood coagulation among overweight adults." dans: European journal of clinical investigation, Vol. 46, Issue 12, pp. 1031-1040, (2016) (PubMed).
Satoh, Hirayama, Takano, Suzuki-Inoue, Sato, Ohta, Nakagomi, Ozaki: "VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets." dans: Thrombosis journal, Vol. 11, Issue 1, pp. 23, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à Multimerin 1