MUTYH Produits
(MutY Homolog (E. Coli) (MUTYH))
Catégories
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories MUTYH en vedette
MUTYH Anticorps
High quality antibodies with extensive validation data.
MUTYH Kits ELISA
Reliable ELISA kits for a wide range of species.
MUTYH Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MUTYH recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP, RNAi
Validations
- (7)
- (6)
N° du produit
ABIN561883
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
N° du produit
ABIN3187926
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, FACS
Validations
- (3)
N° du produit
ABIN653106
Quantité
400 μL
Fiche technique
Fiche technique
MUTYH recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957923
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1742632
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Validations
N° du produit
ABIN1773536
Quantité
96 tests
Fiche technique
Fiche technique
MUTYH recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311668
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311667
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7399868
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MUTYH
: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." dans: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).: "MUTYH and ORAI1 polymorphisms are associated with susceptibility to osteoarthritis in the Chinese Han population." dans: The Journal of international medical research, Vol. 46, Issue 6, pp. 2292-2300, (2019) (PubMed).
: "Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis." dans: Oncotarget, Vol. 8, Issue 20, pp. 32752-32768, (2017) (PubMed).
: "Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain." dans: Human mutation, Vol. 36, Issue 7, pp. 704-11, (2015) (PubMed).
: "Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer." dans: Oxidative medicine and cellular longevity, Vol. 2014, pp. 617351, (2014) (PubMed).
: "Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation." dans: BMC molecular biology, Vol. 15, pp. 17, (2014) (PubMed).
: "Understanding the role of the Q338H MUTYH variant in oxidative damage repair." dans: Nucleic acids research, Vol. 41, Issue 7, pp. 4093-103, (2013) (PubMed).
: "Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells." dans: Carcinogenesis, Vol. 33, Issue 11, pp. 2301-9, (2012) (PubMed).
: "Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells." dans: Oncology letters, Vol. 4, Issue 6, pp. 1203-1208, (2012) (PubMed).
: "p73 protein regulates DNA damage repair." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 12, pp. 4406-14, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à MUTYH
mutY DNA glycosylase (MUTYH), mutY homolog (E. coli) (MUTYH), mutY DNA glycosylase (mutyh), A/G-specific adenine DNA glycosylase-like (LOC100373318), mutY DNA glycosylase (Mutyh), 5730495A01Rik, CYP2C, MGC145569, MUTYH, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, MYH, MyhProtein level used designations for MUTYH
- mutY homolog (E. coli)
- A/G-specific adenine DNA glycosylase
- A/G-specific adenine DNA glycosylase-like
- mutY homolog
- adenine-DNA glycosylase
- mMYH
- mutY homolog alpha
- the full-length form type A, 5' region
- rMYH
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